Neurobiology
Featured publications
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Inflammasome activation under high cholesterol load triggers a protective microglial phenotype while promoting neuronal pyroptosis
de Dios, Cristina; Abadin, Xenia; Roca-Agujetas, Vicente; Jimenez-Martinez, Marina; Morales, Albert;Trullas, Ramon; Mari, Montserrat; Colell, Anna.Reference:Translational Neurodegeneration 2023.
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Molecular basis for maternal inheritance of human mitochondrial DNA
Lee W; Zamudio-Ochoa A; Buchel G; Podlesniy P; Marti Gutierrez N;(...)Mikhalchenko A; Koski A; Trullas R; Mitalipov S; Temiakov D.Reference:Nature Genetics 2023.
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Proteomic profiling reveals mitochondrial dysfunction in the cerebellum of transgenic mice overexpressing DYRK1A, a Down syndrome candidate gene
Ortega, Mireia; De Toma, Ilario; Fernandez-Blanco, Alvaro; Calderon, Anna; Barahona, Lucia;Trullas, Ramon; Sabido, Eduard; Dierssen, Mara.Reference:Frontiers In Molecular Neuroscience 2022.
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Cell-free mitochondrial DNA deletions in idiopathic, but not LRRK2 Parkinson's disease
Puigros, Margalida; Calderon, Anna; Perez-Soriano, Alexandra; de Dios, Cristina; Fernandez, Manel;Colell, Anna; Marti, Maria-Jose; Tolosa, Eduardo; Trullas, Ramon.Reference:Neurobiology Of Disease 2022.
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Cell-Free DNA as a Prognostic Biomarker for Monitoring Muscle-Invasive Bladder Cancer
Carrasco, R; Ingelmo-Torres, M; Gómez, A; Roldán, FL; Ajami, T;(...)Alcaraz, A; Izquierdo, L; Mengual, L; Trullas, R; Rodríguez-Carunchio, L.Reference:International Journal Of Molecular Sciences 2022.
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Ca<sup>2+</sup>-modulated photoactivatable imaging reveals neuron-astrocyte glutamatergic circuitries within the nucleus accumbens
Serra, I; Esparza, J; Delgado, L; Martín-Monteagudo, C; Puigròs, M;Podlesniy, P; Trullás, R; Navarrete, M.Reference:Nature Communications 2022.
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Antioxidants Threaten Multikinase Inhibitor Efficacy against Liver Cancer by Blocking Mitochondrial Reactive Oxygen Species
Cucarull, B; Tutusaus, A; de Frutos, PG; Colell, A; Marí, M;Morales, A; Hernáez-Alsina, T; Reig, M.Reference:Antioxidants 2021.
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Upregulation of brain cholesterol levels inhibits mitophagy in Alzheimer disease
Roca-Agujetas, V; de Dios, C; Abadin, X; Colell, A;Reference:Autophagy 2021.
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Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease
Roca-Agujetas, V; Barbero-Camps, E; de Dios, C; Podlesniy, P; Abadin, X;Morales, A; Marí, M; Trullàs, R; Colell, A.Reference:Molecular Neurodegeneration 2021.
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Decrease of mitochondrial dna copy number in c9als/ftd
Alvarez-Mora, M I; Podlesniy, P; Riazuelo, T; Serra, N; Rodriguez-Revenga, L;Reference:European Journal Of Human Genetics 2020.