Featured publications

• Copper overload worsens the inflammatory response of microglia to amyloid beta (An) by impairing phagocytosis and promoting mitochondrial DNA-mediated NLRP3 inflammasome activation

  Zubillaga, Marlene; Abadin, Xenia; Ivars, Elia; Puigros, Margalida; Trullas, Ramon;

  Bellini, M Jose; Arnal, Nathalie; Colell, Anna.

  Reference:

  Redox Biology 2025.

• Salivary mitochondrial DNA is associated with biomarkers of Alzheimer's disease in cognitively normal older adults

  Cantero, Jose L; Atienza, Mercedes; Podlesniy, Petar; Puigros, Margalida; Trullas, Ramon;

  Reference:

  Translational Psychiatry 2025.

• Reply to: An alternative model for maternal mtDNA inheritance

  Lee, William; Zamudio-Ochoa, Angelica; Buchel, Gina; Podlesniy, Petar; Gutierrez, Nuria Marti;

  Mikhalchenko, Aleksei; Trullas, Ramon; Mitalipov, Shoukhrat; Temiakov, Dmitry.

  Reference:

  NATURE GENETICS 2025.

• Neuroinflammation in Age-Related Neurodegenerative Diseases: Role of Mitochondrial Oxidative Stress

  Abadin, Xenia; de Dios, Cristina; Zubillaga, Marlene; Ivars, Elia; Puigros, Margalida;

  (...)

  Vizuete, Marisa; Vitorica, Javier; Trullas, Ramon; Colell, Anna; Roca-Agujetas, Vicente.

  See complete list of authors

  Reference:

  Antioxidants 2024.

• Mitochondrial DNA deletions in the cerebrospinal fl uid of patients with idiopathic REM sleep behaviour disorder

  Puigros, Margalida; Calderon, Anna; Martin-Ruiz, Daniel; Fernandez, Manel; Munoz-Lopetegi, Amaia;

  (...)

  Gaig, Carles; Colell, Anna; Tolosa, Eduard; Iranzo, Alex; Trullas, Ramon.

  See complete list of authors

  Reference:

  EBioMedicine 2024.

• Quantification of rare somatic single nucleotide variants by droplet digital PCR using SuperSelective primers

  Pablo-Fontecha, Veronica; Hernandez-Illan, Eva; Reparaz, Andrea; Asensio, Elena; Morata, Jordi;

  (...)

  Jover, Rodrigo; Castells, Antoni; Trullas, Ramon; Podlesniy, Petar; Camps, Jordi.

  See complete list of authors

  Reference:

  Scientific Reports 2023.

• Molecular basis for maternal inheritance of human mitochondrial DNA

  Lee, William; Zamudio-Ochoa, Angelica; Buchel, Gina; Podlesniy, Petar; Marti Gutierrez, Nuria;

  (...)

  Mikhalchenko, Aleksei; Koski, Amy; Trullas, Ramon; Mitalipov, Shoukhrat; Temiakov, Dmitry.

  See complete list of authors

  Reference:

  NATURE GENETICS 2023.

• Inflammasome activation under high cholesterol load triggers a protective microglial phenotype while promoting neuronal pyroptosis

  de Dios, Cristina; Abadin, Xenia; Roca-Agujetas, Vicente; Jimenez-Martinez, Marina; Morales, Albert;

  Trullas, Ramon; Mari, Montserrat; Colell, Anna.

  Reference:

  Translational Neurodegeneration 2023.

• Cell-Free DNA as a Prognostic Biomarker for Monitoring Muscle-Invasive Bladder Cancer

  Carrasco, Raquel; Ingelmo-Torres, Mercedes; Gomez, Ascension; Trullas, Ramon; Roldan, Fiorella L;

  (...)

  Moreno, Davinia; Rodriguez-Carunchio, Leonardo; Alcaraz, Antonio; Izquierdo, Laura; Mengual, Lourdes.

  See complete list of authors

  Reference:

  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022.

• Ca²⁺-modulated photoactivatable imaging reveals neuron-astrocyte glutamatergic circuitries within the nucleus accumbens

  Serra, Irene; Esparza, Julio; Delgado, Laura; Martin-Monteagudo, Cristina; Puigros, Margalida;

  Podlesniy, Petar; Trullas, Ramon; Navarrete, Marta.

  Reference:

  Nature Communications 2022.