Featured publications

Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells

Guo Y; Lu X; Chen Y; Rendon B; Mitchell RA;

Cuatrecasas M; Cortés M; Postigo A; Liu Y; Dean DC .

Reference:
Science Advances 2021.
ZEB1 promotes inflammation and progression towards inflammation-driven carcinoma through repression of the DNA repair glycosylase MPG in epithelial cells

de Barrios O; Sanchez-Moral L; Cortés M; Ninfali C; Profitós-Pelejà N;

(...)

Castells A; Maurel J; Salas A; Dean DC; Postigo A .

Reference:
Gut 2019.
ZEB1 protects skeletal muscle from damage and is required for its regeneration

Siles, L; Ninfali, C; Cortes, M; Darling, DS; Postigo, A;

Reference:
Nature Communications 2019.
Regulation of muscle atrophy-related genes by the opposing transcriptional activities of ZEB1/CtBP and FOXO3

Ninfali C; Siles L; Darling D; Postigo A;

Reference:
Nucleic Acids Research 2018.
Mitotic polarization of transcription factors during asymmetric division establishes fate of forming cancer cells

Liu Y; Siles L; Lu X; Dean K; Cuatrecasas M;

Postigo A; Dean D.

Reference:
Nature Communications 2018.
Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles

Cortes, Marlies; Sanchez-Moral, Lidia; de Barrios, Oriol; Fernandez-Acenero, Maria J.; Martinez-Campanario, M. C.;

(...)

Darling, Douglas S.; Gyorffy, Balazs; Lawrence, Toby; Dean, Douglas C.; Postigo, Antonio;.

Reference:
Embo Journal 2017.
ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1

De Barrios O.; Gyorffy B.; Fernández-Aceñero M.J.; Sánchez-Tilló E.; Sánchez-Moral L.;

(...)

Roué G.; Casal J.I.; Darling D.S.; Castells A.; Postigo A..

Reference:
Gut 2017.
Different thresholds of ZEB1 are required for Ras-mediated tumour initiation and metastasis

Liu Y.; Lu X.; Huang L.; Wang W.; Jiang G.;

(...)

Cuatrecasas M.; Chesney J.; Darling D.S.; Postigo A.; Dean D.C..

Reference:
Nature Communications 2014.
The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma

Sanchez-Tillo, E; Fanlo, L; Siles, L; Montes-Moreno, S; Moros, A;

(...)

Martinez, A; Colomer, D; Gyorffy, B; Roue, G; Postigo, A.

Reference:
Cell Death And Differentiation 2014.
ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1

Sanchez-Tillo, Ester; de Barrios, Oriol; Siles, Laura; Amendola, Pier G; Darling, Douglas S;

Cuatrecasas, Miriam; Castells, Antoni; Postigo, Antonio.

Reference:
Clinical Cancer Research 2013.