Featured publications

• Organismal metabolism regulates the expansion of oncogenic PIK3CA mutant clones in normal esophagus

  Herms, A; Colom, B; Piedrafita, G; Kalogeropoulou, A; Banerjee, U;

  (...)

  Fowler, JC; Pol, A; Frezza, C; Vanhaesebroeck, B; Jones, PH.

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  Reference:

  NATURE GENETICS 2024.

• Self-sustaining long-term 3D epithelioid cultures reveal drivers of clonal expansion in esophageal epithelium

  Herms, A; Fernandez-Antoran, D; Alcolea, MP; Kalogeropoulou, A; Banerjee, U;

  (...)

  Mahbubani, K; Saeb-Parsy, K; Lowe, AR; Gerstung, M; Jones, PH.

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  Reference:

  NATURE GENETICS 2024.

• Lipid droplets provide metabolic flexibility for cancer progression

  Safi, R; Menéndez, P; Pol, A;

  Reference:

  FEBS LETTERS 2024.

• Defensive-lipid droplets: Cellular organelles designed for antimicrobial immunity

  Safi, R; Sánchez-Alvarez, M; Bosch, M; Demangel, C; Parton, RG;

  Pol, A.

  Reference:

  IMMUNOLOGICAL REVIEWS 2023.

• Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation

  Morales-Paytuví, F; Fajardo, A; Ruiz-Mirapeix, C; Rae, J; Tebar, F;

  Bosch, M; Enrich, C; Collins, BM; Parton, RG; Pol, A.

  Reference:

  JOURNAL OF CELL BIOLOGY 2023.

• Eukaryotic lipid droplets: metabolic hubs, and immune first responders

  Bosch, M; Pol, A;

  Reference:

  TRENDS IN ENDOCRINOLOGY AND METABOLISM 2022.

• Lipid droplets and the host-pathogen dynamic: FATal attraction?

  Bosch, M; Sweet, MJ; Parton, RG; Pol, A;

  Reference:

  JOURNAL OF CELL BIOLOGY 2021.

• Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense

  Bosch, Marta; Sanchez-Alvarez, Miguel; Fajardo, Alba; Kapetanovic, Ronan; Steiner, Bernhard;

  (...)

  Sweet, Matthew J; Bozza, Patricia T; Gross, Steven P; Parton, Robert G; Pol, Albert.

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  Reference:

  SCIENCE 2020.

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• AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation

  Herms, Albert; Bosch, Marta; Reddy, Babu J N; Schieber, Nicole L; Fajardo, Alba;

  (...)

  Tebar, Francesc; Enrich, Carlos; Parton, Robert G; Gross, Steven P; Pol, Albert.

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  Reference:

  Nature Communications 2015.

• Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites

  Pol, Albert; Gross, Steven P; Parton, Robert G;

  Reference:

  JOURNAL OF CELL BIOLOGY 2014.