Featured publications

• Pan-PPAR agonist lanifibranor improves portal hypertension and hepatic fibrosis in experimental advanced chronic liver disease

  Authors: Boyer-Diaz Z, Aristu-Zabalza P, Andrés-Rozas M, Robert C, Ortega-Ribera M, Fernández-Iglesias A, Broqua P, Junien JL, Wettstein G, Bosch J, Gracia-Sancho J.

  Reference: JOURNAL OF HEPATOLOGY 2021; ():-.

• Novel therapeutics for portal hypertension and fibrosis in chronic liver disease

  Authors: Guixé-Muntet S; Zhu CP; Xie WF; Gracia-Sancho J.

  Reference: PHARMACOLOGY & THERAPEUTICS 2020; 215(107626):107626-.

• Human amniotic stem cells improve hepatic microvascular dysfunction and portal hypertension in cirrhotic rats

  Authors: Pietrosi G, Fernández-Iglesias A, Pampalone M, Ortega-Ribera M, Lozano JJ, García-Calderó H, Abad-Jordà L, Conaldi PG, Parolini O, Vizzini G, Luca A, Bosch J, Gracia-Sancho J.

  Reference: LIVER INTERNATIONAL 2020; 40(10):2500-2514.

• Ischemia/reperfusion injury in the aged liver: The importance of the sinusoidal endothelium in developing therapeutic strategies for the elderly

  Authors: Hide D, Warren A, Fernández-Iglesias A, Maeso-Díaz R, Peralta C, Le Couteur DG, Bosch J, Cogger VC, Gracia-Sancho J.

  Reference: Journals Of Gerontology Series A-Biological Sciences And Medical Sciences 2020; 75(2):268-277.

• Lowering Portal Pressure Improves Outcomes of Patients With Cirrhosis, With or Without Ascites: A Meta-Analysis

  Authors: Turco L, Villanueva C, La Mura V, García-Pagán JC, Reiberger T, Genescà J, Groszmann RJ, Sharma BC, Merkel C, Bureau C, Alvarado E, Abraldes JG, Albillos A, Bañares R, Peck-Radosavljevic M, Augustin S, Sarin SK, Bosch J, García-Tsao G.

  Reference: Clinical Gastroenterology and Hepatology 2020; 18(2):313-327.e6.

• Use of steatotic grafts in liver transplantation: Current status

  Authors: Álvarez-Mercado AI, Gulfo J, Romero Gómez M, Jiménez-Castro MB, Gracia-Sancho J, Peralta C.

  Reference: LIVER TRANSPLANTATION 2019; 25(5):771-786.

• Hepatic microcirculation and mechanisms of portal hypertension

  Authors: Gracia-Sancho J; Marrone G; Fernández-Iglesias A.

  Reference: Nature Reviews Gastroenterology & Hepatology 2019; 16(4):221-234.

• 4 in 1: Antibody-free protocol for isolating the main hepatic cells from healthy and cirrhotic single rat livers

  Authors: Fernández-Iglesias A, Ortega-Ribera M, Guixé-Muntet S, Gracia-Sancho J.

  Reference: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2019; 23(2):877-886.

• New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease

  Authors: Maeso-Díaz R, Boyer-Diaz Z, Lozano JJ, Ortega-Ribera M, Peralta C, Bosch J, Gracia-Sancho J.

  Reference: Cells 2019; 8(9):E1062-.

• Emricasan Ameliorates Portal Hypertension and Liver Fibrosis in Cirrhotic Rats Through a Hepatocyte-Mediated Paracrine Mechanism

  Authors: Gracia-Sancho J, Manicardi N, Ortega-Ribera M, Maeso-Díaz R, Guixé-Muntet S, Fernández-Iglesias A, Hide D, García-Calderó H, Boyer-Díaz Z, Contreras PC, Spada A, Bosch J.

  Reference: Hepatol Commun 2019; 3(7):987-1000.