Translational oncology in upper gastrointestinal cancers
Our inspiration is to bring translational research from the laboratory to the patient, developing more precise and effective treatments for upper gastrointestinal cancers
Current research
Problem
Upper gastrointestinal càncers, including gastric, pancreatic, and biliary tract tumors, are highly aggressive diseases often diagnosed at advanced stages, when curative options are limited. Despite therapeutic advances, survival remains poor. The lack of robust biomarkers and predictive models hampers treatment personalization and early identification of resistance mechanisms, making this an urgent unmet clinical need.
Approach
We combine clinical and translational research to better understand the biology of gastric, pancreatic, and biliary tract cancers. By integrating molecular data, patient-derived models, and liquid biopsy analyses, we uncover biomarkers of response and resistance. Through early-phase clinical trials and biomarker-driven studies, we aim to accelerate the development of precision therapies for upper GI cancers.
Impact
Our goal is to improve survival and quality of life for patients with upper gastrointestinal cancers. Our studies have identified key biomarkers, validated novel therapeutic targets, and implemented innovative approaches such as liquid biopsy for real-time tumor monitoring. Ultimately, we seek to transform molecular knowledge into tangible clinical benefit through translational and precision oncology.
IDIBAPS looks for talented professionals to meet the needs that appear periodically.
Enter