Teresa Macarulla
About me
Dr Teresa Macarulla is Head of the Department of Medical Oncology at Hospital Clínic de Barcelona. She specialises in hepatobiliopancreatic tumours and leads Phase I–III clinical trials focused on targeted therapies. Her work has contributed to FDA and EMA approvals and high-impact publications. She directs a multidisciplinary team integrating clinical and translational research to advance personalised treatment strategies for upper gastrointestinal cancers, including biomarker-driven approaches, liquid biopsy implementation, and investigator-initiated trials
Featured publications
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Comparative genomic landscape of acquired resistance in pancreatic cancer treated with pan-RAS or KRASG12C inhibitors.
Authors:Reference: Annals Of Oncology 2025. -
A Phase II Trial to Assess the Evolution of the KRAS Mutation Load by Liquid Biopsy in Patients With Resectable Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant NALIRIFOX.
Authors:Reference: American Journal Of Clinical Oncology-Cancer Clinical Trials 2025. -
Tumor Treating Fields With Gemcitabine and Nab-Paclitaxel for Locally Advanced Pancreatic Adenocarcinoma: Randomized, Open-Label, Pivotal Phase III PANOVA-3 Study
Authors:Reference: Journal Of Clinical Oncology 2025. -
Atezolizumab Plus Chemotherapy With or Without Bevacizumab in Advanced Biliary Tract Cancer: Clinical and Biomarker Data From the Randomized Phase II IMbrave151 Trial
Authors:Reference: Journal Of Clinical Oncology 2025. -
Genomic profiling unlocks new treatment opportunities for ampullary carcinoma
Authors:Reference: Esmo Open 2025. -
Association of candidate surrogate endpoints with overall survival in advanced biliary tract cancer
Authors:Reference: Journal Of Hepatology 2025. -
Health-related quality of life and performance status with NALIRIFOX versus nab-paclitaxel + gemcitabine in treatment-naive patients with metastatic pancreatic ductal adenocarcinoma: results from the NAPOLI 3 trial
Authors:Reference: Esmo Open 2025. -
Clinical Value of Liquid Biopsy in Patients with FGFR2 Fusion-Positive Cholangiocarcinoma During Targeted Therapy
Authors:Reference: Clinical Cancer Research 2024. -
Facts and Hopes in the Systemic Therapy of Biliary Tract Carcinomas
Authors:Reference: Clinical Cancer Research 2024. -
Motixafortide and Pembrolizumab Combined to Nanoliposomal Irinotecan, Fluorouracil, and Folinic Acid in Metastatic Pancreatic Cancer: The COMBAT/KEYNOTE-202 Trial
Authors:Reference: Clinical Cancer Research 2021.
