Featured publications

• Heterogeneity, crosstalk, and targeting of cancer-associated fibroblasts in cholangiocarcinoma

  Vila, Paula Cantallops; Ravichandra, Aashreya; Lizaso, Alona Agirre; Perugorria, Maria J; Perugorria, Maria J;

  Affo, Silvia.

  Reference:

  HEPATOLOGY 2024.

• Fibroblasts in liver cancer: functions and therapeutic translation

  Affo, Silvia; Filliol, Aveline; Gores, Gregory J; Gores, Gregory J; Schwabe, Robert F;

  Schwabe, Robert F.

  Reference:

  Lancet Gastroenterology & Hepatology 2023.

• Cholangiocarcinoma - novel biological insights and therapeutic strategies

  Ilyas, Sumera I; Ilyas, Sumera I; Affo, Silvia; Goyal, Lipika; Lamarca, Angela;

  Sapisochin, Gonzalo; Yang, Ju Dong; Gores, Gregory J; Gores, Gregory J.

  Reference:

  Nature Reviews Clinical Oncology 2023.

• Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis

  Filliol, Aveline; Saito, Yoshinobu; Nair, Ajay; Dapito, Dianne H; Dapito, Dianne H;

  (...)

  Henderson, Neil C; Henderson, Neil C; Tabas, Ira; Schwabe, Robert F; Schwabe, Robert F.

  See complete list of authors

  Reference:

  NATURE 2022.

• Cancer-associated fibroblasts in intrahepatic cholangiocarcinoma progression and therapeutic resistance

  Ravichandra, Aashreya; Bhattacharjee, Sonakshi; Affo, Silvia;

  Reference:

  Advances in Cancer Research 2022.

• The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver

  Mederacke, Ingmar; Filliol, Aveline; Affo, Silvia; Nair, Ajay; Hernandez, Celine;

  (...)

  Baehre, Heike; Tabas, Ira; Sancho-Bru, Pau; Schwabe, Robert F; Schwabe, Robert F.

  See complete list of authors

  Reference:

  Science Translational Medicine 2022.

• Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations

  Affo, Silvia; Nair, Ajay; Brundu, Francesco; Ravichandra, Aashreya; Bhattacharjee, Sonakshi;

  (...)

  Sia, Daniela; Chen, Xin; Califano, Andrea; Schwabe, Robert F; Schwabe, Robert F.

  See complete list of authors

  Reference:

  CANCER CELL 2021.

• The Role of Cancer-Associated Fibroblasts and Fibrosisin Liver Cancer

  Affo, Silvia; Yu, Le-Xing; Schwabe, Robert F; Schwabe, Robert F;

  Reference:

  Annual Review of Pathology-Mechanisms of Disease 2017.