Featured publications

• Ikzf1 as a novel regulator of microglial homeostasis in inflammation and neurodegeneration

  Ballasch I; García-García E; Vila C; Pérez-González A; Sancho-Balsells A;

  (...)

  Gasull X; Alberch J; Rodríguez MJ; Canals JM; Giralt A .

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  Reference:

  Brain Behavior And Immunity 2023.

• Increased phospho-AKT in blood cells from LRRK2 G2019S mutation carriers

  Garrido A; Pérez-Sisqués L; Simonet C; Campoy-Campos G; Solana-Balaguer J;

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  Tolosa E; Martí MJ; Ezquerra M; Malagelada C; Fernández-Santiago R .

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  Reference:

  Annals Of Neurology 2022.

• GPC3-Unc5 receptor complex structure and role in cell migration

  Akkermans O; Delloye-Bourgeois C; Peregrina C; Carrasquero-Ordaz M; Kokolaki M;

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  Owens RJ; Robinson CV; Castellani V; Del Toro D; Seiradake E .

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  Reference:

  Cell 2022.

• Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington's disease mice

  Pupak A; Singh A; Sancho-Balsells A; Alcalá-Vida R; Espina M;

  Giralt A; Martí E; Ørom UAV; Ginés S; Brito V .

  Reference:

  Cellular And Molecular Life Sciences 2022.

• Translating cell therapies for neurodegenerative diseases: Huntington's disease as a model disorder

  Rosser AE; Busse ME; Gray WP; Badin RA; Perrier AL;

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  Mills LJ; Drew C; Goldman SA; Canals JM; Thompson LM .

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  Reference:

  Brain 2022.

• Huntington’s disease brain-derived small RNAs recapitulate associated neuropathology in mice

  Creus-Muncunill J; Guisado-Corcoll A; Venturi V; Pantano L; Escaramís G;

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  Masana M; Llorens F; Diaz-Lucena D; Pérez-Navarro E; Martí E.

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  Reference:

  Acta Neuropathologica 2021.

• Neuron type-specific increase in lamin B1 contributes to nuclear dysfunction in Huntington’s disease

  Alcalá-Vida R; Garcia-Forn M; Castany-Pladevall C; Creus-Muncunill J; Ito Y;

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  Samarajiwa S; Peiró S; Di Croce L; Narita M; Pérez-Navarro E.

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  Reference:

  Embo Molecular Medicine 2021.

• M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington's disease

  Fernández-García S; Conde-Berriozabal S; García-García E; Gort-Paniello C; Bernal-Casas D;

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  Campa L; Artigas F; Rodríguez MJ; Alberch J; Masana M .

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  Reference:

  Elife 2020.

• Increased translation as a novel pathogenic mechanism in Huntington's disease

  Creus-Muncunill J; Badillos-Rodríguez R; Garcia-Forn M; Masana M; Barriga G;

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  Alberch J; Malagelada C; Delgado-García J; Gruart A; Pérez-Navarro E.

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  Reference:

  Brain 2019.

• Cyclin-Dependent Kinase 5 Dysfunction Contributes to Depressive-like Behaviors in Huntington's Disease by Altering the DARPP-32 Phosphorylation Status in the Nucleus Accumbens

  Brito V; Giralt A; Masana M; Royes A; Espina M;

  Sieiro E; Alberch J; Castañé A; Girault J; Ginés S.

  Reference:

  Biological Psychiatry 2019.