Pathophysiology and treatment of neurodegenerative disorders
Featured publications
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Targeted neuronal reprogramming rescues memory and neural synchrony in Alzheimer's disease
Galán-Ganga, M; Rodríguez-Navarro, I; Zaballa, S; Ramón-Lainez, A; Gómez-Rivada, N;(...)Rabadán, MA; Alberch, J; Rodríguez, MJ; del Toro, D; Giralt, A.Reference:Molecular Biomedicine 2026.
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Structurally exclusive Teneurin complexes orchestrate divergent programs in early cortical development
Berbeira-Santana, M; Peregrina, C; Okuda, K; Zhou, JC; Carrasquero-Ordaz, M;(...)Pardon, E; Steyaert, J; Nägerl, UV; del Toro, D; Seiradake, E.Reference:Nature Communications 2026.
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Restoration of CB1 receptor function in hippocampal GABAergic neurons rescues memory deficits in Huntington's disease models
Di Franco, N; de Tena, IB; Sanchez-Ruiz, A; Pereda-Velarde, A; Enfedaque, F;(...)Vazquez-Oliver, A; Ozaita, A; Guzmán, M; Perea, G; Ginés, S.Reference:Translational Neurodegeneration 2025.
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Alterations of the IKZF1-IKZF2 tandem in immune cells of schizophrenia patients regulate associated phenotypes
Ballasch, I; López-Molina, L; Galán-Ganga, M; Sancho-Balsells, A; Rodríguez-Navarro, I;(...)Alberch, J; del Toro, D; Arranz, B; Canals, JM; Giralt, A.Reference:Journal of Neuroinflammation 2024.
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Expansion of the neocortex and protection from neurodegeneration by in vivo transient reprogramming
Shen, YR; Zaballa, S; Bech, X; Sancho-Balsells, A; Rodríguez-Navarro, I;(...)Abad, M; Serrano, M; Klein, R; Giralt, A; del Toro, D.Reference:Cell Stem Cell 2024.
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m6A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts
Pupak, A; Rodríguez-Navarro, I; Sathasivam, K; Singh, A; Essmann, A;(...)Pinto, RM; Bates, GP; Orom, UAV; Marti, E; Brito, V.Reference:EMBO REPORTS 2024.
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Small RNAs in plasma extracellular vesicles define biomarkers of premanifest changes in Huntington's disease
Herrero-Lorenzo, M; Pérez-Pérez, J; Escaramís, G; Martínez-Horta, S; Pérez-González, R;Rivas-Asensio, E; Kulisevsky, J; Gámez-Valero, A; Martí, E.Reference:Journal of Extracellular Vesicles 2024.
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RTP801 mediates transneuronal toxicity in culture via extracellular vesicles
Solana-Balaguer, J; Martín-Flores, N; Garcia-Segura, P; Campoy-Campos, G; Pérez-Sisqués, L;(...)Fernández-Irigoyen, J; Santamaría, E; Pérez-Navarro, E; Alberch, J; Malagelada, C.Reference:Journal of Extracellular Vesicles 2023.
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M2 cortex circuitry and sensory-induced behavioral alterations in Huntington's Disease: role of superior colliculus
Conde-Berriozabal, S; García-Gilabert, L; García-García, E; Sitjà-Roqueta, L; López-Gil, X;(...)Boudjadja, MB; Soria, G; Rodríguez, MJ; Alberch, J; Masana, M.Reference:JOURNAL OF NEUROSCIENCE 2023.
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Cell Therapy for Huntington's Disease: Learning from Failure
Rosser, AE; Busse, M; Badin, RA; Canals, JM; Wheelock, V;Perrier, AL; Gray, W; Thompson, L; Goldman, S.Reference:MOVEMENT DISORDERS 2021.
