Antoni Castells

About me

Featured publications

• Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

  Authors:

  Fernandez-Rozadilla, Ceres; Timofeeva, Maria; Chen, Zhishan; Law, Philip; Thomas, Minta;

  (...)

  Tomlinson, Ian; Zheng, Wei; Dunlop, Malcolm; Houlston, Richard; Peters, Ulrike.

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  Reference: Nature Genetics 2023.

• The present and future of gastroenterology and hepatology: an international SWOT analysis (the GASTROSWOT project)

  Authors:

  de-Madaria, Enrique; Mira, Jose J; Carrillo, Irene; Afif, Waqqas; Ang, Daphne;

  (...)

  Savarino, Edoardo, V; Singh, Vikesh K; Vargo, John; Charabaty, Aline; Drenth, Joost P H.

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  Reference: Lancet Gastroenterology & Hepatology 2022.

• Colon capsule endoscopy versus CT colonography in FIT-positive colorectal cancer screening subjects: a prospective randomised trial-the VICOCA study

  Authors:

  Gonzalez-Suarez, Begona; Pages, Mario; Araujo, Isis Karina; Romero, Cristina; Rodriguez de Miguel, Cristina;

  (...)

  Llach, Josep; Serra-Burriel, Miquel; Cardenas, Andres; Balaguer, Francesc; Castells, Antoni.

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  Reference: Bmc Medicine 2020.

• Eflornithine plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis

  Authors:

  Burke, Carol A; Dekker, Evelien; Lynch, Patrick; Samadder, N Jewel; Balaguer, Francesc;

  (...)

  Weiss, Jennifer M; Gryfe, Robert; Rustgi, Anil K; Syngal, Sapna; Cohen, Alfred.

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  Reference: New England Journal Of Medicine 2020.

• White-light Endoscopy is Adequate for Lynch Syndrome Surveillance in a Randomized and Non-inferiority Study

  Authors:

  Rivero-Sanchez, Liseth; Arnau-Collell, Coral; Herrero, Jesus; Remedios, David; Cubiella, Joaquin;

  (...)

  Jung, Gerhard; Castells, Antoni; Llach, Josep; Balaguer, Francesc; Pellise, Maria.

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  Reference: Gastroenterology 2020.

• Identification and validation of microRNA profiles in fecal samples for detection of colorectal cancer

  Authors:

  Duran-Sanchon, Saray; Moreno, Lorena; Auge, Josep M; Serra-Burriel, Miquel; Cuatrecasas, Miriam;

  (...)

  Lacy, Antonio; Pellise, Maria; Jose Lozano, Juan; Gironella, Meritxell; Castells, Antoni.

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  Reference: Gastroenterology 2020.

• Risk Stratification for Advanced Colorectal Neoplasia According to Fecal Hemoglobin Concentration in a Colorectal Cancer Screening Program

  Authors:

  Auge, Josep M; Pellise, Maria; Escudero, Jose M; Hernandez, Cristina; Andreu, Montserrat;

  (...)

  Guayta, Rafael; Filella, Xavier; Molina, Rafael; Jimenez, Wladimiro; Castells, Antoni.

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  Reference: Gastroenterology 2014.

• Risk of advanced proximal neoplasms according to distal colorectal findings: based strategies

  Authors:

  Castells, Antoni; Bessa, Xavier; Quintero, Enrique; Bujanda, Luis; Cubiella, Joaquin;

  (...)

  Manuel Blanco, Jose; Sastre, Rocio; Ferrandiz, Juan; Jose Gonzalez-Hernandez, Ma; Andreu, Montserrat.

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  Reference: Journal Of The National Cancer Institute 2013.

• Identification of Lynch Syndrome Among Patients With Colorectal Cancer

  Authors:

  Moreira, Leticia; Balaguer, Francesc; Lindor, Noralane; de la Chapelle, Albert; Hampel, Heather;

  (...)

  Moreno, Victor; Andreu, Montserrat; de Leon, Maurizio Ponz; Rustgi, Anil K; Castells, Antoni.

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  Reference: Jama-Journal Of The American Medical Association 2012.

• Colonoscopy versus fecal immunochemical testing in colorectal-cancer screening

  Authors:

  Quintero, Enrique; Castells, Antoni; Bujanda, Luis; Cubiella, Joaquin; Salas, Dolores;

  (...)

  Diaz-Tasende, Jose; Herreros-de-Tejada, Alberto; Poves, Carmen; Santander, Cecilio; Gonzalez-Navarro, Andres.

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  Reference: New England Journal Of Medicine 2012.

Featured Projects

• Identificación de nuevos biomarcadores para la prevención del cáncer colorrectal

  Principal investigator: Antoni Castells Garangou

  Funder: Asociación Española Contra el Cáncer

  Code: AECC_GrupoEstable13

  Duration: 01/10/2013 - 30/09/2019

• Randomized controlled trial of colonoscopy versus fecal immunochemical testing in colorectal cancer screening. The COLONPREV study

  Principal investigator: Antoni Castells Garangou

  Funder: Asociación Española Contra el Cáncer

  Code: AECC_EstClinicos21

  Duration: 01/01/2021 - 30/09/2026

• Detección de mirna en heces como nueva estrategia de cribado del cáncer colorrectal: identificación y validación en población de riesgo medio

  Principal investigator: Antoni Castells Garangou

  Funder: Ministerio de Economía y Competitividad

  Code: MINECO_PE14

  Duration: 01/01/2015 - 31/12/2019

• Caracterización genómica del síndrome de Lynch mediante secuenciación de nueva generación: correlación con el perfil transcriptómico y epigenómico

  Principal investigator: Antoni Castells Garangou

  Funder: Ministerio de Economia y Competitividad (MINECO)

  Code: MICINN_PN10

  Duration: 01/01/2011 - 31/12/2014

• Hipermetilación de la región promotora de los genes MLH1, MGMT, CDKN2A, RASSF1A, CDX1 y SFRP1 en mucosa colorrectal no tumoral como factor favorecedor del desarrollo del cáncer colorrectal

  Principal investigator: Antoni Castells Garangou

  Funder: Ministerio de Educación, Cultura y Deporte

  Code: MEC_PN07

  Duration: 02/07/2007 - 31/12/2010