David Brea

About me

Featured publications

• Neuronal-ILC2 interactions regulate pancreatic glucagon and glucose homeostasis

  Authors:

  Sestan, Marko -; Raposo, Bruno; Rendas, Miguel; Brea, David; Pirzgalska, Roksana;

  (...)

  Ribeiro, Helder; Carvalho, Tania; Wueest, Stephan; Konrad, Daniel; Veiga-Fernandes, Henrique.

  See complete list of authors

  Reference: SCIENCE 2025.

• Meningeal interleukin-17-producing T cells mediate cognitive impairment in a mouse model of salt-sensitive hypertension

  Authors:

  Santisteban, Monica M; Schaeffer, Samantha; Anfray, Antoine; Faraco, Giuseppe; Brea, David;

  (...)

  Racchumi, Gianfranco; Waisman, Ari; Park, Laibaik; Anrather, Josef; Iadecola, Costantino.

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  Reference: NATURE NEUROSCIENCE 2024.

• Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila

  Authors:

  Simoes, Anabel R; Neto, Marta; Alves, Carolina S; Santos, Mariana B; Fernandez-Hernandez, Ismael;

  Veiga-Fernandes, Henrique; Brea, David; Dura, Irene; Encinas, Juan M; Rhiner, Christa.

  Reference: DEVELOPMENTAL CELL 2022.

• Stroke affects intestinal immune cell trafficking to the central nervous system

  Authors:

  Brea, David; Poon, Carrie; Benakis, Corinne; Lubitz, Gabrielle; Murphy, Michelle;

  Iadecola, Costantino; Anrather, Josef.

  Reference: BRAIN BEHAVIOR AND IMMUNITY 2021.

• Distinct Commensal Bacterial Signature in the Gut Is Associated With Acute and Long-Term Protection From Ischemic Stroke

  Authors:

  Benakis, Corinne; Poon, Carrie; Lane, Diane A; Brea, David; Sita, Giulia;

  Moore, Jamie; Murphy, Michelle; Racchumi, Gianfranco; Iadecola, Costantino; Anrather, Josef.

  Reference: STROKE 2020.

• Endogenous Protection from Ischemic Brain Injury by Preconditioned Monocytes

  Authors:

  Garcia-Bonilla, Lidia; Brea, David; Benakis, Corinne; Lane, Diane A; Murphy, Michelle;

  Moore, Jamie; Racchumi, Gianfranco; Jiang, Xinran; Iadecola, Costantino; Anrather, Josef.

  Reference: JOURNAL OF NEUROSCIENCE 2018.

• Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response

  Authors:

  Faraco, Giuseppe; Brea, David; Garcia-Bonilla, Lidia; Wang, Gang; Racchumi, Gianfranco;

  (...)

  Sugiyama, Yukio; Murphy, Michelle; Voss, Henning; Anrather, Joseph; Ladecola, Costantino.

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  Reference: NATURE NEUROSCIENCE 2018.

• Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

  Authors:

  Benakis, Corinne; Brea, David; Caballero, Silvia; Faraco, Giuseppe; Moore, Jamie;

  (...)

  Racchumi, Gianfranco; Lingo, Lilan; Pamer, Eric G; Iadecola, Costantino; Anrather, Josef.

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  Reference: NATURE MEDICINE 2016.

• Study of Protein Expresion in Peri-Infarct Tissue after Cerebral Ischemia

  Authors:

  Brea, David; Agulla, Jesus; Staes, An; Gevaert, Kris; Campos, Francisco;

  Sobrino, Tomas; Blanco, Miguel; Davalos, Antoni; Castillo, Jose; Ramos-Cabrer, Pedro.

  Reference: Scientific Reports 2015.

• Regulatory T cells modulate inflammation and reduce infarct volume in experimental brain ischaemia

  Authors:

  Brea, David; Agulla, Jesus; Rodriguez-Yanez, Manuel; Barral, David; Ramos-Cabrer, Pedro;

  Campos, Francisco; Almeida, Angeles; Davalos, Antoni; Castillo, Jose.

  Reference: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2014.

Featured Projects

• La interacción Neuroinmune en el infarto cerebral (IRONICAL).

  Principal investigator: David Brea López

  Funder: Agencia Estatal de Investigación, Ministerio de Ciencia e Innovación de España

  Duration: 01/09/2023 - 31/08/2026

• Descubriendo los secretos del cráneo: el papel de la médula ósea del cráneo en la respuesta inmune al infarto cerebral.

  Principal investigator: David Brea López

  Funder: Ministerio de Ciencia e Innovación

  Code: CNS2023-143852

  Duration: 01/01/2024 - 31/12/2026

• Stroke-induced insulin resistance: an important risk factor for cardio and cerebrovascular complications (SUNRISE).

  Principal investigator: David Brea López

  Funder: Fundacio la Marato TV3

  Code: 202305- 10

  Duration: 01/01/2024 - 31/12/2026