Eduard Parellada

About me

Featured publications

• Effects of the PAM of mGluR2, JNJ-46356479, on brain apoptotic protein levels in a mouse model of schizophrenia

  Authors:

  Olivares-Berjaga, David; Martinez-Pinteno, Albert; Rodriguez, Natalia; Madero, Santiago; Prohens, Llucia;

  Martinez-Serrano, Irene; Mas, Sergi; Moren, Constanza; Parellada, Eduard; Gasso, Patricia.

  Reference: Progress In Neuro-Psychopharmacology & Biological Psychiatry 2024.

• Early treatment with JNJ-46356479, a mGluR2 modulator, improves behavioral and neuropathological deficits in a postnatal ketamine mouse model of schizophrenia

  Authors:

  Martinez-Pinteno, A; Rodriguez, N; Olivares, D; Madero, S; Gomez, M;

  (...)

  Garcia-Rizo, C; Mas, S; Moren, C; Parellada, E; Gasso, P.

  See complete list of authors

  Reference: Biomedicine & Pharmacotherapy 2023.

• Systematic Review of the Therapeutic Role of Apoptotic Inhibitors in Neurodegeneration and Their Potential Use in Schizophrenia

  Authors:

  Moren, Constanza; Treder, Nina; Martinez-Pinteno, Albert; Rodriguez, Natalia; Arbelo, Nestor;

  Madero, Santiago; Gomez, Marta; Mas, Sergi; Gasso, Patricia; Parellada, Eduard.

  Reference: Antioxidants 2022.

• Glutamate and microglia activation as a driver of dendritic apoptosis: a core pathophysiological mechanism to understand schizophrenia

  Authors:

  Parellada, E; Gassó, P;

  Reference: Translational Psychiatry 2021.

• Microarray gene-expression study in fibroblast and lymphoblastoid cell lines from antipsychotic-naïve first-episode schizophrenia patients

  Authors:

  Gasso, Patricia; Mas, Sergi; Rodriguez, Natalia; Boloc, Daniel; Garcia-Cerro, Susana;

  Bernardo, Miquel; Lafuente, Amalia; Parellada, Eduard.

  Reference: Journal Of Psychiatric Research 2017.

• Apoptotic markers in cultured fibroblasts correlate with brain metabolites and regional brain volume in antipsychotic-naive first-episode schizophrenia and healthy controls

  Authors:

  Batalla, A; Bargallo, N; Gasso, P; Molina, O; Pareto, D;

  Mas, S; Roca, J M; Bernardo, M; Lafuente, A; Parellada, E.

  Reference: Translational Psychiatry 2015.

• Neurotoxic/neuroprotective activity of haloperidol, risperidone and paliperidone in neuroblastoma cells

  Authors:

  Gasso, Patricia; Mas, Sergi; Molina, Oriol; Bernardo, Miquel; Lafuente, Amalia;

  Parellada, Eduard.

  Reference: Progress In Neuro-Psychopharmacology & Biological Psychiatry 2012.

• A 4-year dopamine transporter (DAT) imaging study in neuroleptic-naive first episode schizophrenia patients

  Authors:

  Mane, Anna; Gallego, Judith; Lomena, Francisco; Javier Mateos, Jose; Fernandez-Egea, Emilio;

  Horga, Guillermo; Cot, Albert; Pavia, Javier; Bernardo, Miguel; Parellada, Eduard.

  Reference: Psychiatry Research-Neuroimaging 2011.

• Differential brain glucose metabolic patterns in antipsychotic-naive first-episode schizophrenia with and without auditory verbal hallucinations

  Authors:

  Horga, Guillermo; Parellada, Eduard; Lomena, Francisco; Fernandez-Egea, Emilio; Mane, Anna;

  Falcon, Carles; Konova, Anna B; Pavia, Javier; Ros, Domenec; Bernardo, Miguel.

  Reference: Journal Of Psychiatry & Neuroscience 2011.

• The resting and activation issue of hypofrontality:: A single photon emission computed tomography study in neuroleptic-naive and neuroleptic-free schizophrenic female patients

  Authors:

  Parellada, E; Catafau, AM; Bernardo, M; Lomeña, F; Catarineu, S;

  González-Monclús, E.

  Reference: Biological Psychiatry 1998.

Featured Projects

• Marcadores glutamatérgicos y respuesta antipsicótica inicial en pacientes con primer episodio psicótico (PEP) y en un modelo animal de esquizofrenia

  Principal investigator: Eduard Parellada Rodon, Patricia Gassó Astorga

  Funder: Instituto de Salud Carlos III

  Code: PI21/00552

  Duration: 01/01/2022 - 31/12/2024

• Estudio convergente en modelo celular, animal y humano del efecto y mecanismos de acción de la clozapina e inhibidores de glutamato en los síntomas negativos-cognitivos de la esquizofrenia

  Principal investigator: Eduard Parellada Rodon, Patricia Gassó Astorga

  Funder: Instituto de Salud Carlos III

  Code: PI18/01005

  Duration: 01/01/2019 - 30/06/2023

• Cellular, molecular, genetic and cognitive-behavioral characterization of the antiapoptotic effect of clozapine and glutamate inhibitors in a postnatal ketamine animal model of schizophrenia

  Principal investigator: Eduard Parellada Rodon

  Funder: Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer

  Code: FCRB_PB2_2018

  Duration: 01/01/2018 - 31/12/2022

• Apoptosis y cambios estructurales progresivos en pacientes con un primer episodio de esquizofrenia: estudio longitudinal y multimodal de neuroimagen y biología molecular.

  Principal investigator: Eduard Parellada Rodon

  Funder: Instituto de Salud Carlos III

  Code: PI080055.

  Duration: 01/01/2009 - 31/12/2011

• Neuroanatomía funcional de las alucinaciones auditivas en la esquizofrenia: estudio multidisciplinar con PET-F18-FDG en el episodio psicótico agudo, durante la remisión y durante la estimulación acústica

  Principal investigator: Eduard Parellada Rodon

  Funder: Fundació La Marató de TV3

  Code: 012410

  Duration: 01/01/2002 - 31/12/2003