Francisco Díaz-Castro

Featured publications

• Multiscale mitochondrial cristae remodeling links Opa1 downregulation to reduced OXPHOS capacity in aged hearts

  Authors:

  Molina-Riquelme, Isidora; Barrientos, Gonzalo; Breitsprecher, Leonhard; Gomez, Wileidy; Diaz-Castro, Francisco;

  (...)

  Garrido-Olivares, Luis; Verdejo, Hugo E; Psathaki, Olympia Ekaterini; Busch, Karin B; Eisner, Veronica.

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  Reference: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2026.

• Deletion of Mfn2 in endothelial cells triggers a mitohormetic response that improves systemic metabolism and healthspan in mice

  Authors:

  Chivite, Inigo; Monelli, Erika; Munar-Gelabert, Margalida; Gomez-Valades, Alicia G; Alvarado-Diaz, Abdiel;

  (...)

  Nogueiras, Rube N; Horvath, Tamas L; De Bock, Katrien; Graupera, Mariona; Claret, Marc.

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  Reference: Cell Metabolism 2026.

• Interplay between the brain and adipose tissue: a metabolic conversation

  Authors:

  Diaz-Castro, Francisco; Morselli, Eugenia; Claret, Marc;

  Reference: EMBO REPORTS 2024.

• A single bout of resistance exercise triggers mitophagy, potentially involving the ejection of mitochondria in human skeletal muscle

  Authors:

  Diaz-Castro, Francisco; Tunon-Suarez, Mauro; Rivera, Patricia; Botella, Javier; Cancino, Jorge;

  (...)

  Zbinden-Foncea, Hermann; Nielsen, Joachim; Henriquez-Olguin, Carlos; Morselli, Eugenia; Castro-Sepulveda, Mauricio.

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  Reference: Acta Physiologica 2024.

• Mitofusin-2 induced by exercise modifies lipid droplet-mitochondria communication, promoting fatty acid oxidation in male mice with NAFLD

  Authors:

  Borquez, Juan Carlos; Diaz-Castro, Francisco; Pino-de La Fuente, Francisco; Espinoza, Karla; Figueroa, Ana Maria;

  (...)

  Pol, Albert; Zorzano, Antonio; Cortes, Victor; Hernandez-Alvarez, Maria Isabel; Troncoso, Rodrigo.

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  Reference: METABOLISM-CLINICAL AND EXPERIMENTAL 2024.

• Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism

  Authors:

  Avalos, Yenniffer; Paz Hernandez-Caceres, Maria; Lagos, Pablo; Pinto-Nunez, Daniela; Rivera, Patricia;

  (...)

  Parra, Valentina; Budini, Mauricio; Burgos, Patricia, V; Criollo, Alfredo; Morselli, Eugenia.

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  Reference: Cell Death & Disease 2022.

• Association Between Adipose Tissue Characteristics and Metabolic Flexibility in Humans: A Systematic Review

  Authors:

  Glaves, Alice; Diaz-Castro, Francisco; Farias, Javiera; Ramirez-Romero, Rodrigo; Galgani, Jose E;

  Fernandez-Verdejo, Rodrigo.

  Reference: Front Nutr 2021.

• Differential Effects of Oleic and Palmitic Acids on Lipid Droplet-Mitochondria Interaction in the Hepatic Cell Line HepG2

  Authors:

  Eynaudi, Andrea; Diaz-Castro, Francisco; Borquez, Juan Carlos; Bravo-Sagua, Roberto; Parra, Valentina;

  Troncoso, Rodrigo.

  Reference: Front Nutr 2021.

• The fasting-feeding metabolic transition regulates mitochondrial dynamics

  Authors:

  Castro-Sepulveda, Mauricio; Morio, Beatrice; Tunon-Suarez, Mauro; Jannas-Vela, Sebastian; Diaz-Castro, Francisco;

  Rieusset, Jennifer; Zbinden-Foncea, Hermann.

  Reference: FASEB JOURNAL 2021.

• Mifepristone for Treatment of Metabolic Syndrome: Beyond Cushing's Syndrome

  Authors:

  Diaz-Castro, Francisco; Monsalves-Alvarez, Matias; Rojo, Leonel E; del Campo, Andrea; Troncoso, Rodrigo;

  Reference: Frontiers in Pharmacology 2020.