Gregori Casals

Research group

Translational research group in new therapeutic and diagnostic strategies in liver diseases Accredited researcher (R3A)

casals@clinic.cat 0000-0002-3271-1371

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Featured publications

Mesoporous silica coated CeO2 nanozymes with combined lipid-lowering and antioxidant activity induce long-term improvement of the metabolic profile in obese Zucker rats

Authors: Parra-Robert, Marina; Zeng, Muling; Shu, Ying; Fernandez-Varo, Guillermo; Perramon, Meritxell; Desai, Diti; Chen, Junhao; Guo, Dongdong; Zhang, Xu; Morales-Ruiz, Manuel; Rosenholm, Jessica M.; Jimenez, Wladimiro; Puntes, Victor; Casals, Eudald; Casals, Gregori;.

Reference: Nanoscale 2021.
Bespoken nanoceria: A new effective treatment in experimental hepatocellular carcinoma

Authors: Fernández-Varo G, Perramón M, Carvajal S, Oró D, Casals E, Boix L, Oller L, Macías-Muñoz L, Marfà S, Casals G, Morales-Ruiz M, Casado P, Cutillas PR, Bruix J, Navasa M, Fuster J, Garcia-Valdecasas JC, Pavel MC, Puntes V, Jiménez W .

Reference: Hepatology 2020.
Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo

Authors: Madiraju, Anila K.; Qiu, Yang; Perry, Rachel J.; Rahimi, Yasmeen; Zhang, Xian-Man; Zhang, Dongyan; Camporez, Joao-Paulo G.; Cline, Gary W.; Butrico, Gina M.; Kemp, Bruce E.; Casals, Gregori; Steinberg, Gregory R.; Vatner, Daniel F.; Petersen, Kitt F.; Shulman, Gerald, I;.

Reference: Nature Medicine 2018.
Intrinsic and Extrinsic Properties Affecting Innate Immune Responses to Nanoparticles: The Case of Cerium Oxide.

Authors: Casals E, Gusta MF, Piella J, Casals G, Jiménez W, Puntes V .

Reference: Frontiers In Immunology 2017.
Cerium oxide nanoparticles reduce steatosis, portal hypertension and display antiinflammatory properties in rats with liver fibrosis

Authors: Oró D, Yudina T, Fernández-Varo G, Casals E, Reichenbach V, Casals G, González de la Presa B, Sandalinas S, Carvajal S, Puntes V, Jiménez W .

Reference: Journal Of Hepatology 2016.
Microwave-assisted derivatization: Application to steroid profiling by gas chromatography/mass spectrometry

Authors: Casals, Gregori; Marcos, Josep; Pozo, Oscar J.; Alcaraz, Jose; Jesus Martinez de Osaba, Maria; Jimenez, Wladimiro;.

Reference: Journal Of Chromatography B-Analytical Technologies In The Biomedical And Life Sciences 2014.
Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes

Authors: Casals, Gregori; Ros, Josefa; Sionis, Alessandro; Davidson, Mercy M; Morales-Ruiz, Manuel; Jimenez, Wladimiro.

Reference: American Journal Of Physiology-Heart And Circulatory Physiology 2009.

Featured Projects

Evaluation of antioxidant and anti-inflammatory properties of cerium oxide nanoparticles as novel therapeutic strategy in hepatic steatosis.

Principal investigator: Gregori Casals Mercadal

Funder: CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (Sede o evento); Fondo de Investigación Sanitaria

Duration: 01/01/2016 - 01/01/2018
Cerium oxide nanoparticles as a new therapeutic tool for tissue regeneration in liver diseases

Principal investigator: Víctor Franco Puntes

Funder: CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (Sede o evento); Fundació La Marató de TV3

Duration: 01/01/2013 - 01/01/2015
Basic and translational implications of the functional and molecular alterations of the hepatic endothelium in cirrhosis

Principal investigator: Manuel Morales Ruiz

Funder: CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (Sede)

Duration: 01/01/2011 - 01/01/2013
Pathophysiological role of activated liver endothelial cells in cirrhosis. Possible therapeutical implications

Principal investigator: Manuel Morales Ruiz

Funder: CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (Sede o evento); Dirección General de Investigación Científica (Ministerio de Educación y Ciencia)

Duration: 01/01/2008 - 01/01/2010
Aplicaciones de la genómica en la identificación de dianas terapéuticas específicas para el endotelio hepático en la cirrosis, función fisiopatológica de VEGF.

Principal investigator: Manuel Morales Ruiz

Funder: CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (Sede o evento); Fondo de Investigación Sanitaria

Duration: 01/01/2005 - 01/01/2007

Gregori Casals

Research group

Featured publications

Mesoporous silica coated CeO2 nanozymes with combined lipid-lowering and antioxidant activity induce long-term improvement of the metabolic profile in obese Zucker rats

Bespoken nanoceria: A new effective treatment in experimental hepatocellular carcinoma

Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo

Intrinsic and Extrinsic Properties Affecting Innate Immune Responses to Nanoparticles: The Case of Cerium Oxide.

Cerium oxide nanoparticles reduce steatosis, portal hypertension and display antiinflammatory properties in rats with liver fibrosis

Microwave-assisted derivatization: Application to steroid profiling by gas chromatography/mass spectrometry

Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes

Featured Projects

Evaluation of antioxidant and anti-inflammatory properties of cerium oxide nanoparticles as novel therapeutic strategy in hepatic steatosis.

Cerium oxide nanoparticles as a new therapeutic tool for tissue regeneration in liver diseases

Basic and translational implications of the functional and molecular alterations of the hepatic endothelium in cirrhosis

Pathophysiological role of activated liver endothelial cells in cirrhosis. Possible therapeutical implications

Aplicaciones de la genómica en la identificación de dianas terapéuticas específicas para el endotelio hepático en la cirrosis, función fisiopatológica de VEGF.

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