Sabela Lens

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Featured publications

• Tracking B cell immunity during perturbation of hepatitis B infection induced by treatment withdrawal

  Authors:

  Lens, Sabela; Burton, Alice R; Davies, Jessica; Locatelli, Maelle; Garcia-Lopez, Mireia;

  (...)

  Novikov, Nikolai; Fletcher, Simon P; Forns, Xavier; Perez-del-Pulgar, Sofia; Maini, Mala K.

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  Reference: GUT 2025.

• Incidence and Clinical Significance of Recompensation After HCV Cure

  Authors:

  Semmler, Georg; Lens, Sabela; Hidalgo, Alvaro; Lopez, Sonia Alonso; Perez-Perez, Maria;

  (...)

  Genesca, Joan; Banares, Rafael; Forns, Xavier; Fernandez, Inmaculada; Mandorfer, Mattias.

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  Reference: Clinical Gastroenterology and Hepatology 2025.

• Determinants of HBsAg Loss After Nucleos(t)ide Discontinuation in a Prospective Cohort of HBeAg-Negative Caucasian Patients

  Authors:

  Pocurull, Anna; Broquetas, Teresa; Hoyas, Elena; Rodriguez, Manuel; Miquel, Mireia;

  (...)

  Suarez, Emilio; Buti, Maria; Forns, Xavier; Carrion, Jose A; Lens, Sabela.

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  Reference: LIVER INTERNATIONAL 2025.

• HBV Suppression by Nucleos(t)ide Analogues Reduces PD-1 Expression on Liver-Resident T Cells

  Authors:

  Garcia-Lopez, Mireia; Lens, Sabela; Pallett, Laura J; Pocurull, Anna; Leonel, Thais;

  (...)

  Lin, Jonah; Gehring, Adam J; Maini, Mala K; Forns, Xavier; Perez-del-Pulgar, Sofia.

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  Reference: LIVER INTERNATIONAL 2025.

• Real-life effectiveness of sofosbuvir/velpatasvir/voxilaprevir in hepatitis C patients previously treated with sofosbuvir/velpatasvir or glecaprevir/pibrentasvir

  Authors:

  Ruiz-Cobo, Juan Carlos; Llaneras, Jordi; Forns, Xavier; Gallego Moya, Adolfo; Conde Amiel, Isabel;

  (...)

  Bernal-Monterde, Vanesa; Delgado, Manuel; Turnes, Juan; Lens, Sabela; Buti, Maria.

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  Reference: ALIMENTARY PHARMACOLOGY & THERAPEUTICS 2024.

• Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS

  Authors:

  Pallett, Laura J; Swadling, Leo; Diniz, Mariana; Maini, Alexander A A; Schwabenland, Marius;

  (...)

  Gilroy, Derek W W; Dorner, Marcus; Bengsch, Bertram; Schurich, Anna; Maini, Mala K K.

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  Reference: NATURE 2023.

• Non-invasive tests for clinically significant portal hypertension after HCV cure

  Authors:

  Semmler, Georg; Lens, Sabela; Meyer, Elias L; Baiges, Anna; Alvardo-Tapias, Edilmar;

  (...)

  Hernandez-Gea, Virginia; Reiberger, Thomas; Bosch, Jaume; Pagan, Juan Carlos Garcia; Mandorfer, Mattias.

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  Reference: JOURNAL OF HEPATOLOGY 2022.

• HCV microelimination in harm reduction centres has benefits beyond HCV cure but is hampered by high reinfection rates

  Authors:

  Lens, Sabela; Miralpeix, Anna; Galvez, Mont; Martro, Elisa; Gonzalez, Noemi;

  (...)

  Saludes, Veronica; Reyes-Uruena, Juliana; Majo, Xavier; Colom, Joan; Forns, Xavier.

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  Reference: JHEP Rep 2022.

• Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients

  Authors:

  Garcia-Lopez, Mireia; Lens, Sabela; Pallett, Laura J; Testoni, Barbara; Rodriguez-Tajes, Sergio;

  (...)

  Koutsoudakis, George; Zoulim, Fabien; Maini, Mala K; Forns, Xavier; Perez-del-Pulgar, Sofia.

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  Reference: JOURNAL OF HEPATOLOGY 2021.

• Clinical outcome and hemodynamic changes following HCV eradication with oral antiviral therapy in patients with clinically significant portal hypertension

  Authors:

  Lens, Sabela; Baiges, Anna; Alvarado-Tapias, Edilmar; LLop, Elba; Martinez, Javier;

  (...)

  Hernandez-Gea, Virginia; Bosch, Jaume; Villanueva, Candid; Carlos Garcia-Pagan, Juan; Forns, Xavier.

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  Reference: JOURNAL OF HEPATOLOGY 2020.

Featured Projects

• Análisis transcriptómico espacial de las interacciones virus-huésped y la respuesta al tratamiento en la hepatitis crónica Delta (SPACE-D)

  Principal investigator: Sabela Lens García, Xavier Forns Bernhardt

  Funder: Instituto de Salud Carlos III (ISCIII)

  Code: PI25/01234

  Duration: 01/01/2026 - 31/12/2028

• TherVacB: A therapeutic vaccine to cure hepatitis B

  Principal investigator: Xavier Forns Bernhardt

  Funder: European Commission

  Code: 848223

  Duration: 01/01/2020 - 31/12/2024

  Web: https://www.thervacb.eu/

• Eliminación de VHC y diagnóstico y vinculación de pacientes VHD en el área sanitariadel Hospital Clínic de Barcelona (HepCD-Clinic)

  Principal investigator: Sabela Lens García

  Funder: Asociación Española para el Estudio del Hígado - Gilead Sciences

  Duration: 01/01/2026 - 31/12/2027

• Bulevirtide for Hepatitis Delta: clinical impact on liver disease and non-invasive correlates with portal hypertension

  Principal investigator: Sabela Lens García

  Funder: Gilead Sciences

  Duration: 01/01/2026 - 31/12/2027

• Red C17 Viral Hepatitis Care 2030: Innovación en la detección y equidad asistencial en hepatitis vírica

  Principal investigator: Sabela Lens García

  Funder: Generalitat de Catalunya

  Duration: 01/01/2026 - 31/12/2027