Sofía Pérez-Del-Pulgar
Featured publications
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Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture
Authors: Álvarez EG, Demeulemeester J, Otero P, Jolly C, García-Souto D, Pequeño-Valtierra A, Zamora J, Tojo M, Temes J, Baez-Ortega A, Rodriguez-Martin B, Oitaben A, Bruzos AL, Martínez-Fernández M, Haase K, Zumalave S, Abal R, Rodríguez-Castro J, Rodriguez-Casanova A, Diaz-Lagares A, Li Y, Raine KM, Butler AP, Otero I, Ono A, Aikata H, Chayama K, Ueno M, Hayami S, Yamaue H, Maejima K, Blanco MG, Forns X, Rivas C, Ruiz-Bañobre J, Pérez-Del-Pulgar S, Torres-Ruiz R, Rodriguez-Perales S, Garaigorta U, Campbell PJ, Nakagawa H, Van Loo P, Tubio JMC .Reference: Nature Communications 2021. -
Modeling hepatitis C virus kinetics during liver transplantation reveals the role of the liver in virus clearance
Authors: Shekhtman L, Navasa M, Sansone N, Crespo G, Subramanya G, Chung TL, Cardozo-Ojeda EF, Pérez-Del-Pulgar S, Perelson AS, Cotler SJ, Forns X, Uprichard SL, Dahari H .Reference: Elife 2021. -
Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients
Authors: García-López M, Lens S, Pallett LJ, Testoni B, Rodríguez-Tajes S, Mariño Z, Bartres C, García-Pras E, Leonel T, Perpiñán E, Lozano JJ, Rodríguez-Frías F, Koutsoudakis G, Zoulim F, Maini MK, Forns X, Pérez-Del-Pulgar S .Reference: Journal Of Hepatology 2021. -
Hepatitis C virus intrinsic molecular determinants may contribute to the development of cholestatic hepatitis after liver transplantation
Authors: Gambato M, Gregori J, Quer J, Koutsoudakis G, González P, Caro-Pérez N, García-Cehic D, García-González N, González-Candelas F, Esteban JI, Crespo G, Navasa M, Forns X, Pérez-Del-Pulgar S .Reference: Journal Of General Virology 2019. -
Hepatitis C virus early kinetics and resistance-associated substitution dynamics during antiviral therapy with direct-acting antivirals.
Authors: Perpiñán E, Caro-Pérez N, García-González N, Gregori J, González P, Bartres C, Soria ME, Perales C, Lens S, Mariño Z, Londoño MC, Ariza X, Koutsoudakis G, Quer J, González-Candelas F, Forns X, Pérez-Del-Pulgar S .Reference: Journal Of Viral Hepatitis 2018. -
Phylogenetic analysis of an epidemic outbreak of acute hepatitis C in HIV-infected patients by ultra-deep pyrosequencing
Authors: Caro-Pérez N; Martínez-Rebollar M; Gregori J; Quer J; González P; Gambato M; García-González N; González-Candelas F; Costa J; Esteban J; Mallolas J; Forns X; Laguno M; Pérez-del-Pulgar S.Reference: Journal Of Clinical Virology 2017. -
Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture
Authors: Harak, Christian; Meyrath, Max; Romero-Brey, Ines; Schenk, Christian; Gondeau, Claire; Schult, Philipp; Esser-Nobis, Katharina; Saeed, Mohsan; Neddermann, Petra; Schnitzler, Paul; Gotthardt, Daniel; Perez-del-Pulgar, Sofia; Neumann-Haefelin, Christoph; Thimme, Robert; Meuleman, Philip; Vondran, Florian W. R.; De Francesco, Raffaele; Rice, Charles M.; Bartenschlager, Ralf; Lohmann, Volker;.Reference: Nature Microbiology 2017. -
Hepatitis C Virus RNA Persists in Liver Explants of Most Patients Awaiting Liver Transplantation Treated With an Interferon-Free Regimen
Authors: Gambato M, Pérez-Del-Pulgar S, Hedskog C, Svarovskia ES, Brainard D, Denning J, Curry MP, Charlton M, Caro-Pérez N, Londoño MC, Koutsoudakis G, Forns X .Reference: Gastroenterology 2016. -
Clinical relevance of the study of hepatitis B virus covalently closed circular DNA
Authors: Kumar R., Pérez-del-Pulgar S., Testoni B., Lebossé F., Zoulim F..Reference: Liver International 2016. -
Hepatitis C virus infection inhibits P-body granule formation in human livers
Authors: Pérez-Vilaró G., Fernández-Carrillo C., Mensa L., Miquel R., Sanjuan X., Forns X., Pérez-Del-Pulgar S., Díez J..Reference: Journal Of Hepatology 2015.
Featured Projects
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Study of cccDNA persistence during HBV infection in vivo, and in vitro using a bioreactor that mimics the liver microenvironment
Principal investigator: Sofia Perez del Pulgar GallartFunder: Instituto de Salud Carlos III (ISCIII)Code: PI16/00111Duration: 01/01/2017 - 31/12/2019 -
Virological and immunological factors associated with hepatitis C and hepatitis B virus infection recurrence after treatment discontinuation
Principal investigator: Xavier Forns BernhardtFunder: Gilead EspañaDuration: 07/03/2016 - 06/03/2018 -
TherVacB: A therapeutic vaccine to cure hepatitis B
Principal investigator: Xavier Forns BernhardtCode: 848223Duration: 01/01/2020 - 31/12/2024 -
Interplay between HBV, HDV and host factors: impact on liver disease progression (InBDeL)
Principal investigator: Sofia Perez del Pulgar GallartCode: PI19/00036Duration: 01/01/2020 - 31/12/2022 -
Viral and immune factors associated with antiviral treatment and hepatitis C recurrence after liver transplantation
Principal investigator: Sofia Perez del Pulgar GallartCode: PI13/00155Duration: 01/01/2014 - 30/03/2017