Yaroslau Compta

About me

Featured publications

• Barcelona Progressive Supranuclear Palsy (PSP) Registry: Clinical, Oculomotor, and Cerebrospinal Fluid Markers; from Suggestive to Definite Cases

  Authors:

  Painous, C; Fernández, M; Cámara, A; Alba-Arbalat, S; Soto, M;

  (...)

  Pérez-Montesino, J; De Mena, L; Naranjo, L; Ruiz-García, R; Compta, Y.

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  Reference: Movement Disorders 2025.

• Sensitivity and specificity of a seed amplification assay for diagnosis of multiple system atrophy: a multicentre cohort study

  Authors:

  Ma, YH; Farris, CM; Weber, S; Schade, S; Nguyen, H;

  (...)

  Kang, UJ; Compta, Y; Svenningsson, P; Mollenhauer, B; Concha-Marambio, L.

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  Reference: Lancet Neurology 2024.

• Midbrain and pons MRI shape analysis and its clinical and CSF correlates in degenerative parkinsonisms: a pilot study

  Authors:

  Painous, C; Pascual-Diaz, S; Muñoz-Moreno, E; Sánchez, V; Pariente, JC;

  (...)

  Tio, M; Rios, J; Mart, MJ; Bargall, N; Compta, Y.

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  Reference: European Radiology 2023.

• Trial of Deferiprone in Parkinson's Disease

  Authors:

  Devos, D; Labreuche, J; Rascol, O; Corvol, JC; Duhamel, A;

  (...)

  Duce, JA; Cabantchik, I; Defebvre, L; Deplanque, D; Moreau, C.

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  Reference: New England Journal Of Medicine 2022.

• Combined CSF α-SYN RT-QuIC, CSF NFL and midbrain-pons planimetry in degenerative parkinsonisms: From bedside to bench, and back again

  Authors:

  Compta, Y; Painous, C; Soto, M; Pulido-Salgado, M; Fernandez, M;

  (...)

  Perez-Soriano, A; Zaro, I; Munoz, E; Marti, MJ; Valldeoriola, F.

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  Reference: Parkinsonism & Related Disorders 2022.

• Prediagnostic motor and non-motor symptoms in progressive supranuclear palsy: The step-back PSP study

  Authors:

  Painous, C; Martí, MJ; Simonet, C; Garrido, A; Valldeoriola, F;

  Muñoz, E; Cámara, A; Compta, Y.

  Reference: Parkinsonism & Related Disorders 2020.

• Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria.

  Authors:

  Hoeglinger, Guenter U; Respondek, Gesine; Stamelou, Maria; Kurz, Carolin; Josephs, Keith A;

  (...)

  van Eimeren, Thilo; Wenning, Gregor K; Boxer, Adam L; Golbe, Lawrence I; Litvan, Irene.

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  Reference: Movement Disorders 2017.

• Correlates of cerebrospinal fluid levels of oligomeric-and total-α-synuclein in premotor, motor and dementia stages of Parkinson’s disease

  Authors:

  Compta, Yaroslau; Valente, Tony; Saura, Josep; Segura, Barbara; Iranzo, Alex;

  (...)

  Fortea, Juan; Buongiorno, Mariateresa; Luis Molinuevo, Jose; Bargallo, Nuria; Jose Marti, Maria.

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  Reference: Journal Of Neurology 2015.

• Lewy- and Alzheimer-type pathologies in Parkinson''s disease dementia: which is more important?

  Authors:

  Compta, Yaroslau; Parkkinen, Laura; O'Sullivan, Sean S; Vandrovcova, Jana; Holton, Janice L;

  (...)

  Kallis, Constantinos; Williams, David R; de Silva, Rohan; Lees, Andrew J; Revesz, Tamas.

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  Reference: Brain 2011.

• Cerebrospinal hypocretin, daytime sleepiness and sleep architecture in Parkinson's disease dementia

  Authors:

  Compta, Yaroslau; Santamaria, Joan; Ratti, Luca; Tolosa, Eduardo; Iranzo, Alex;

  Munoz, Esteban; Valldeoriola, Francesc; Casamitjana, Roser; Rios, Jose; Marti, Maria J.

  Reference: Brain 2009.

Featured Projects

• The SYNCHIP study - Clinically Adaptable Pipette-Driven Microchamber Array for Quantitative Diagnosis of Synucleinopathies: Moving on Beyond Conventional Seed Amplification Assays

  Principal investigator: Yaroslau Compta Hirnyj

  Funder: Michael J. Fox Foundation for Parkinson’s Research

  Code: INT_MJF_Spring_25

  Duration: 01/11/2025 - 31/10/2027

• Cell-Specific Epigenomic Changes in iPSC-Derived Oligodendrocytes from MSA Patients: Effects of α-Synuclein Fibril Exposure in a Disease-Specific Model

  Principal investigator: Yaroslau Compta Hirnyj

  Funder: King Baudouin Foundation

  Code: INT_KBF_MSA_24

  Duration: 22/05/2025 - 21/05/2025

• Translational Platform for MSA: Elucidation of Disease-mechanisms and Drug discovery

  Funder: European Comission

  Code: CE_FLAG-ERA_21

  Duration: 01/04/2022 - 31/03/2025

• Clinical Cohort study with biomarkers study of prediagnostic cases and health education program in established disease..

  Principal investigator: Yaroslau Compta Hirnyj

  Funder: La MARATO - TV3

  Code: 202009-10_PSP REGISTRY

  Duration: 12/03/2020 - 29/03/2024

• Amplificación de autoagregación de alfa-sinucleína y 4R-tau en tejido cerebral y líquido cerebrospinal mediante RTQuIC como biomarcador diferencial de parkinsonismos degenerativos.

  Principal investigator: Yaroslau Compta Hirnyj

  Funder: ISCIII

  Duration: 01/01/2018 - 31/10/2021