Featured publications

• Mutations in the small nuclear RNA gene RNU2-2 cause a severe neurodevelopmental disorder with prominent epilepsy

  Greene, D; De Wispelaere, K; Lees, J; Codina-Solà, M; Jensson, BO;

  (...)

  O'Donoghue, M; Pérez-Jurado, LA; Freson, K; Mumford, AD; Turro, E.

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  Reference:

  NATURE GENETICS 2025.

• Mesoporous Silica-Encapsulated Cerium Oxide Nanozymes and Quercetin for Synergistic ROS-Modulated Downregulation of Inflammatory Cytokines

  Zhou, Shanlei; Zhang, Yu; Casals, Eudald; Zeng, Muling; Morales-Ruiz, Manuel;

  Liu, Qingshi; Zhang, Bo; Casals, Gregori.

  Reference:

  International Journal of Nanomedicine 2025.

• Tcf20 deficiency is associated with increased liver fibrogenesis and alterations in mitochondrial metabolism in mice and humans

  Cordoba-Jover, Bernat; Ribera, Jordi; Portoles, Irene; Lecue, Elena; Rodriguez-Vita, Juan;

  (...)

  Pinyol, Roser; Huguet-Pradell, Julia; Melgar-Lesmes, Pedro; Jimenez, Wladimiro; Morales-Ruiz, Manuel.

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  Reference:

  LIVER INTERNATIONAL 2023.

• RNF41 orchestrates macrophage-driven fibrosis resolution and hepatic regeneration

  Moreno-Lanceta, A; Medrano-Bosch, M; Fundora, Y; Perramón, M; Aspas, J;

  (...)

  Baena, S; Fondevila, C; Edelman, ER; Jiménez, W; Melgar-Lesmes, P.

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  Reference:

  Science Translational Medicine 2023.

• Mesoporous silica coated CeO2 nanozymes with combined lipid-lowering and antioxidant activity induce long-term improvement of the metabolic profile in obese Zucker rats

  Parra-Robert, Marina; Zeng, Muling; Shu, Ying; Fernandez-Varo, Guillermo; Perramon, Meritxell;

  (...)

  Rosenholm, Jessica M; Jimenez, Wladimiro; Puntes, Victor; Casals, Eudald; Casals, Gregori.

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  Reference:

  Nanoscale 2021.

• Treatment of Hepatic Fibrosis in Mice Based on Targeted Plasmonic Hyperthermia

  Ribera, J; Vilches, C; Sanz, V; de Miguel, I; Portolés, I;

  (...)

  Prat, E; Nunes, V; Jiménez, W; Quidant, R; Morales-Ruiz, M.

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  Reference:

  ACS Nano 2021.

• Bespoken nanoceria: A new effective treatment in experimental hepatocellular carcinoma

  Fernandez-Varo, Guillermo; Perramon, Meritxell; Carvajal, Silvia; Oro, Denise; Casals, Eudald;

  (...)

  Fuster, Josep; Garcia-Valdecasas, Juan Carlos; Pavel, Mihai C; Puntes, Victor; Jimenez, Wladimiro.

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  Reference:

  HEPATOLOGY 2020.

• Akt-mediated foxo1 inhibition is required for liver regeneration

  Pauta, M; Rotllan, N; Fernandez-Hernando, A; Langhi, C; Ribera, J;

  (...)

  Ford, DA; Baldan, A; Birnbaum, MJ; Morales-Ruiz, M; Fernandez-Hernando, C.

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  Reference:

  HEPATOLOGY 2016.

• Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates

  Lee, Monica Y; Luciano, Amelia K; Ackah, Eric; Rodriguez-Vita, Juan; Bancroft, Tara A;

  Eichmann, Anne; Simons, Michael; Kyriakides, Themis R; Morales-Ruiz, Manuel; Sessa, William C.

  Reference:

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2014.