Research lines

• Endothelial Dysfunction in the Pathogenesis of Portal Hypertension

  Directed by Virginia Hernández Gea

  Her research centers on the role of endothelial dysfunction in the development of portal hypertension and portal vein thrombosis, with a strong emphasis on the mechanistic understanding of vascular liver diseases. By integrating translational and experimental approaches, her work aims to identify novel therapeutic targets and discover clinically relevant biomarkers to improve diagnosis, risk stratification, and patient outcomes. She also has strong interest in developoing preclinical models of vascular liver disease.

• Pathophysiology, diagnosis and treatment of portal hypertension

  Directed by Juan Carlos García‑Pagán

  His research research is centered on the pathophysiology, diagnosis and treatment of portal hypertension and its complications in patients with cirrhosis and vascular liver diseases, including variceal bleeding, hepatic hemodynamics, and vascular disorders such as Budd-Chiari syndrome. His work aims to advance both invasive and non-invasive strategies to understand and manage increased portal pressure and related clinical outcomes.

• Frailty & Sarcopenia in Liver Diseases Hepatic Encephalopathy

  Directed by Anna Baiges Aznar

  Her research focus on developing new therapies for hepatic encephalopathy and how functional status and physiologic reserve affect prognosis, improve risk prediction, and optimize care before, during, and after transplant to enhance patient resilience and survival. 

• Critical management of patients with Liver Disease

  Directed by Enric Reverter Segura

  Research focused on improving the management and outcomes of critically ill patients with advanced liver disease through early identification of organ failure, hemodynamic optimization, and tailored organ support. The goal is to better understand the mechanisms of acute decompensation and acute-on-chronic liver failure to develop targeted, evidence-based therapies in the ICU setting.