Clínic Barcelona

An epigenetic study identifies a connection between cell longevity and cancer

Researchers from IDIBAPS and the University of Barcelona (UB) lead a study, published today in the prestigious journal Nature Genetics, which reveals an unexpected connection between epigenetic changes associated with lymphocytes’ maturation and those observed in cancer. Both processes share similar changes in large regions of the genome. The work, led by Dr. Iñaki Martín-Subero, researcher in the Pathology, Pharmacology and Microbiology Department at UB and IDIBAPS, is the first in analyze the epigenome during cell maturation of B lymphocytes, the immune system cells responsible of the antibodies production, and provides epigenetic maps of each step in this process.