Clínic Barcelona

Mitochondrial DNA deletions predict Parkinson’s before symptoms appear

A study led by researchers from the CSIC, IDIBAPS-Hospital Clínic Barcelona and the University of Barcelona (UB) indicates that the presence of mitochondrial DNA with mutations in which one or more bases of the DNA sequence in the cerebrospinal fluid is lost predicts the appearance of Parkinson’s motor symptoms and cognitive disorders.

Image of a fibroblast from a patient with Parkinson’s disease. Mitochondria appear in green. Fragments of damaged mitochondria are in red. Some of these fragments of damaged mitochondria are released into the extracellular space. (IIBB-CSIC)

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