Alba Simats
Research group
- Cerebrovascular diseases Junior researcher (R2B-IIBB-CSIC)
About me
Early-career independent researcher at the Spanish National Research Council (IIBB-CSIC) specialized in neuroimmunology and innate immune memory after ischemic stroke. Her research focuses on neuro-immune interactions, immunometabolic reprogramming, and the cellular mechanisms driving post-stroke systemic inflammation and peripheral organ dysfunction. She has published in high-impact journals including Cell and Nature Neuroscience, and in 2026 established her independent research line.
Her work focuses on how stroke reshapes peripheral immunity and brain–body communication, and on developing therapies to modulate maladaptive immune responses and secondary complications.
Featured publications
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Heart-brain axis in health and disease: role of innate and adaptive immunity
Authors:Reference: CARDIOVASCULAR RESEARCH 2024. -
Innate immune memory after brain injury drives inflammatory cardiac dysfunction
Authors:Reference: CELL 2024. -
Perspective Review of Myeloid Immune Cell Responses and Poststroke Immunosuppression
Authors:Reference: STROKE 2023. -
T cells modulate the microglial response to brain ischemia
Authors:Reference: eLife 2022. -
Systemic inflammation after stroke: implications for post-stroke comorbidities
Authors:Reference: EMBO Molecular Medicine 2022. -
Ceruletide and Alpha-1 Antitrypsin as a Novel Combination Therapy for Ischemic Stroke
Authors:Reference: Neurotherapeutics 2022. -
Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery
Authors:Reference: Jove-Journal of Visualized Experiments 2021. -
Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke
Authors:Reference: Nature Reviews Neurology 2020. -
CCL23: a new CC chemokine involved in human brain damage
Authors:Reference: JOURNAL OF INTERNAL MEDICINE 2018. -
MAPK-activated protein kinase 2-deficiency causes hyperacute tumor necrosis factor-induced inflammatory shock.
Authors:Reference: BMC Physiology 2014.
