Joan-Marc Servitja

About me

Featured publications

• Direct reprogramming of human fibroblasts into insulin-producing cells using transcription factors

  Authors:

  Fontcuberta-PiSunyer, M; García-Alamán, A; Prades, É; Téllez, N; Alves-Figueiredo, H;

  (...)

  Novials, A; Servitja, JM; Vidal, J; Gomis, R; Gasa, R.

  See complete list of authors

  Reference: Commun Biol 2023.

• High Intensity Interval Training reduces hypoglycemic events compared with continuous aerobic training in individuals with type 1 diabetes: HIIT and hypoglycemia in type 1 diabetes

  Authors:

  Murillo, S; Brugnara, L; Servitja, JM; Novials, A;

  Reference: Diabetes & Metabolism 2022.

• BACE2 suppression in mice aggravates the adverse metabolic consequences of an obesogenic diet

  Authors:

  Díaz-Catalán, D; Alcarraz-Vizán, G; Castaño, C; de Pablo, S; Rodríguez-Comas, J;

  (...)

  Servitja, JM; Fernández-Pérez, A; Vallejo, M; Claret, M; Ramírez, S.

  See complete list of authors

  Reference: Molecular Metabolism 2021.

• 4-Phenylbutyrate (PBA) treatment reduces hyperglycemia and islet amyloid in a mouse model of type 2 diabetes and obesity

  Authors:

  de Pablo, Sara; Rodriguez-Comas, Julia; Diaz-Catalan, Daniela; Alcarraz-Vizan, Gema; Castano, Carlos;

  Moreno-Vedia, Juan; Montane, Joel; Parrizas, Marcelina; Servitja, Joan-Marc; Novials, Anna.

  Reference: Scientific Reports 2021.

• Alpha1-antitrypsin ameliorates islet amyloid-induced glucose intolerance and β-cell dysfunction

  Authors:

  Rodríguez-Comas, J; Moreno-Vedia, J; Obach, M; Castaño, C; de Pablo, S;

  (...)

  Novials, A; Servitja, JM; Mestre, A; Horrillo, R; Costa, M.

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  Reference: Molecular Metabolism 2020.

• Stress-Induced MicroRNA-708 Impairs β-Cell Function and Growth.

  Authors:

  Rodriguez-Comas, Julia; Moreno-Asso, Alba; Moreno-Vedia, Juan; Martin, Merce; Castano, Carlos;

  (...)

  Montane, Joel; Fillat, Cristina; Gasa, Rosa; Novials, Anna; Servitja, Joan-Marc.

  See complete list of authors

  Reference: Diabetes 2017.

• BACE2 suppression promotes β-cell survival and function in a model of type 2 diabetes induced by human islet amyloid polypeptide overexpression.

  Authors:

  Alcarraz-Vizan, Gema; Castano, Carlos; Visa, Montse; Montane, Joel; Servitja, Joan-Marc;

  Novials, Anna.

  Reference: Cellular And Molecular Life Sciences 2017.

• Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control.

  Authors:

  Ramirez, Sara; Gomez-Valades, Alicia G; Schneeberger, Marc; Varela, Luis; Haddad-Tovolli, Roberta;

  (...)

  Servitja, Joan-Marc; Horvath, Tamas L; Gomis, Ramon; Zorzano, Antonio; Claret, Marc.

  See complete list of authors

  Reference: Cell Metabolism 2017.

• Islet amyloid polypeptide exerts a novel autocrine action in b-cell signaling and proliferation

  Authors:

  Visa, Montse; Alcarraz-Vizan, Gema; Montane, Joel; Cadavez, Lisa; Castano, Carlos;

  Luisa Villanueva-Penacarrillo, Maria; Servitja, Joan-Marc; Novials, Anna.

  Reference: Faseb Journal 2015.

• Circulating miR-192 and miR-193b are markers of prediabetes and are modulated by an exercise intervention

  Authors:

  Párrizas M.; Brugnara L.; Esteban Y.; González-Franquesa A.; Canivell S.;

  (...)

  Cussó R.; Cadefau J.; García-Roves P.; Servitja J.; Novials A..

  See complete list of authors

  Reference: Journal Of Clinical Endocrinology & Metabolism 2015.

Featured Projects

• Inter-organ cross-talk and type 2 diabetes: effects of circulating exosomes on pancreatic islets

  Principal investigator: Anna Maria Novials Sarda, Joan Marc Servitja Duque

  Funder: Instituto de Salud Carlos III

  Code: PI20/00658

  Duration: 01/01/2021 - 31/12/2023

• Benchtop NMR for Lab-On-Chip (BLOC)

  Principal investigator: Joan Marc Servitja Duque

  Funder: European Commission

  Code: 863037

  Duration: 01/01/2020 - 31/12/2023

  Web: https://blocproject.eu/

• BACE2, una nueva diana terapéutica para el tratamiento de la diabetes tipo 2 y la obesidad.

  Principal investigator: Joan Marc Servitja Duque, Anna Maria Novials Sarda

  Funder: Instituto de Salud Carlos III

  Code: PI17/00879

  Duration: 01/01/2018 - 31/12/2020

• Nuevas estrategias para el tratamiento de la diabetes: intervención sobre el estrés de retículo endoplásmico y la inflamación inducidos por los depósitos de amiloide en el islote pancreático.

  Principal investigator: Joan Marc Servitja Duque, Anna Maria Novials Sarda

  Funder: Instituto de Salud Carlos III

  Code: PI14/00447

  Duration: 01/01/2015 - 31/12/2017

• Potential protective effects of an anti-inflammatory molecule on pancreatic beta-cells.

  Principal investigator: Joan Marc Servitja Duque, Anna Maria Novials Sarda

  Funder: Instituto Grifols, S.A.

  Duration: 01/01/2013