Manuel Morales-Ruiz

Research group

Biomarkers and laboratory precision medicine in hepatology, metabolism, and rare diseases (HEMERA-Lab) Group leader (R4)

morales@clinic.cat 0000-0002-9074-2272

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Featured publications

Cerium Oxide Nanoparticles: A New Therapeutic Tool in Liver Diseases

Authors:
Casals, Gregori; Perramon, Meritxell; Casals, Eudald; Portoles, Irene; Fernandez-Varo, Guillermo;

Morales-Ruiz, Manuel; Puntes, Victor; Jimenez, Wladimiro.

Reference: Antioxidants 2021.
Treatment of Hepatic Fibrosis in Mice Based on Targeted Plasmonic Hyperthermia

Authors:
Ribera, J; Vilches, C; Sanz, V; de Miguel, I; Portolés, I;

(...)

Prat, E; Nunes, V; Jiménez, W; Quidant, R; Morales-Ruiz, M.

Reference: ACS Nano 2021.
Cerium oxide nanoparticles improve liver regeneration after acetaminophen-induced liver injury and partial hepatectomy in rats

Authors:
Cordoba-Jover, Bernat; Arce-Cerezo, Altamira; Ribera, Jordi; Pauta, Montse; Oro, Denise;

(...)

Fernandez-Varo, Guillermo; Casals, Eudald; Puntes, Victor; Jimenez, Wladimiro; Morales-Ruiz, Manuel.

Reference: JOURNAL OF NANOBIOTECHNOLOGY 2019.
An integrative method to predict signalling perturbations for cellular transitions

Authors:
Zaffaroni, Gaia; Okawa, Satoshi; Morales-Ruiz, Manuel; del Sol, Antonio;

Reference: NUCLEIC ACIDS RESEARCH 2019.
A SMALL POPULATION OF LIVER ENDOTHELIAL CELLS UNDERGOES ENDOTHELIAL TO MESENCHYMAL TRANSITION IN RESPONSE TO CHRONIC LIVER INJURY.

Authors:
Ribera, Jordi; Pauta, Montse; Melgar-Lesmes, Pedro; Cordoba, Bernat; Bosch, Anna;

(...)

Rodrigo-Torres, Daniel; Sancho-Bru, Pau; Mira, Aurea; Jimenez, Wladimiro; Morales-Ruiz, Manuel.

Reference: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 2017.
The Role of Akt in Chronic Liver Disease and Liver Regeneration

Authors:
Morales-Ruiz, Manuel; Santel, Ansgar; Ribera, Jordi; Jimenez, Wladimiro;

Reference: SEMINARS IN LIVER DISEASE 2017.
Utility of galectin-3 in predicting post-infarct remodeling after acute myocardial infarction based on extracellular volume fraction mapping

Authors:
Perea, Rosario J; Morales-Ruiz, Manuel; Ortiz-Perez, Jose T; Bosch, Xavier; Andreu, David;

(...)

Donnelly, James; Jimenez, Wladimiro; Mira, Aurea; Mont, Lluis; Berruezo, Antonio.

Reference: INTERNATIONAL JOURNAL OF CARDIOLOGY 2016.
Akt-mediated foxo1 inhibition is required for liver regeneration

Authors:
Pauta, M; Rotllan, N; Fernandez-Hernando, A; Langhi, C; Ribera, J;

(...)

Ford, DA; Baldan, A; Birnbaum, MJ; Morales-Ruiz, M; Fernandez-Hernando, C.

Reference: HEPATOLOGY 2016.
Overexpression of angiopoietin-2 in rats and patients with liver fibrosis. Therapeutic consequences of its inhibition

Authors:
Pauta, Montse; Ribera, Jordi; Melgar-Lesmes, Pedro; Casals, Gregori; Rodriguez-Vita, Juan;

(...)

Bataller, Ramon; Michelena, Javier; Altamirano, Jose; Jimenez, Wladimiro; Morales-Ruiz, Manuel.

Reference: LIVER INTERNATIONAL 2015.
Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates

Authors:
Lee, Monica Y; Luciano, Amelia K; Ackah, Eric; Rodriguez-Vita, Juan; Bancroft, Tara A;

Eichmann, Anne; Simons, Michael; Kyriakides, Themis R; Morales-Ruiz, Manuel; Sessa, William C.

Reference: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2014.

Featured Projects

Nuevos mecanismos moleculares y nuevas estrategias terapéuticas aplicables a la conservación de la función hepática y a la mejora de la enfermedad hepática crónica

Principal investigator: Manuel Morales Ruiz

Funder: DGICYT (Dirección General de Investigación Científica y Técnica)

Code: PID2019-105502RB-100

Duration: 01/01/2020 - 31/12/2022
Estimulacion de la regeneracion funcional de higados cirroticos mediante la normalizacion vascular intrahepatica y la modulacion de dianas de akt

Principal investigator: Manuel Morales Ruiz

Funder: DGICYT (Dirección General de Investigación Científica y Técnica)

Code: SAF2016-75358-R

Duration: 30/12/2016 - 31/12/2020

Manuel Morales-Ruiz

Research group

Featured publications

Featured Projects

Nuevos mecanismos moleculares y nuevas estrategias terapéuticas aplicables a la conservación de la función hepática y a la mejora de la enfermedad hepática crónica

Estimulacion de la regeneracion funcional de higados cirroticos mediante la normalizacion vascular intrahepatica y la modulacion de dianas de akt

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