
Raquel Sanchez-Valle
Neurology Head of DepartmentAbout me
I completed my training as a neurologist at the Hospital Clínic de Barcelona (2000) and my PhD degree on Biopathology in Medicine at the University of Barcelona (UB) (2003). After this, I obtained a Rio Hortega fellowship (ISCIII, Spanish Ministry of Health) in Behavioural neurology at IDIBAPS. I accomplished a short-term postdoctoral scholarship at the Memory and Aging Center- University of California San Francisco, directed by Dr. Bruce Miller (2006). Back in Barcelona, I became the Group Leader of the Alzheimer’s Disease and other Cognitive Disorders group at the IDIBAPS and Associate professor at the UB (2018). Currently, I am the Head of the Neurology Service at the Hospital Clínic de Barcelona.
Featured publications
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Loss of brainstem white matter predicts onset and motor neuron symptoms in C9orf72 expansion carriers: a GENFI study
Authors: Pérez-Millan A, Borrego-Écija S, van Swieten JC, Jiskoot L, Moreno F, Laforce R, Graff C, Masellis M, Tartaglia MC, Rowe JB, Borroni B, Finger E, Synofzik M, Galimberti D, Vandenberghe R, de Mendonça A, Butler CR, Gerhard A, Ducharme S, Le Ber I, Santana I, Pasquier F, Levin J, Otto M, Sorbi S, Tiraboschi P, Seelaar H, Langheinrich T, Rohrer JD, Sala-Llonch R, Sánchez-Valle R, Genetic FTD Initiative, GENFI.Reference: Journal Of Neurology 2023. -
The APOE4 effect: Structural brain differences in Alzheimer's disease according to the age at symptom onset
Authors: Forno G, Contador J, Pérez-Millan A, Guillen N, Falgàs N, Sarto J, Tort-Merino A, Castellví M, Bosch B, Fernández-Villullas G, Balasa M, Antonell A, Sala-Llonch R, Sanchez-Valle R, Hornberger M, Lladó A .Reference: European Journal Of Neurology 2023. -
Classifying Alzheimer's disease and frontotemporal dementia using machine learning with cross-sectional and longitudinal magnetic resonance imaging data
Authors: Pérez-Millan A, Contador J, Juncà-Parella J, Bosch B, Borrell L, Tort-Merino A, Falgàs N, Borrego-Écija S, Bargalló N, Rami L, Balasa M, Lladó A, Sánchez-Valle R, Sala-Llonch R .Reference: Human Brain Mapping 2023. -
Design and validation of the 1-week memory battery for assessing episodic memory and accelerated long-term forgetting in cognitively unimpaired subjects
Authors: Rami L, León M, Valech N, Coll-Padrós N, Bosch B, Olives J, Salinero A, Pérez-Millan A, Molinuevo JL, Sánchez-Valle R, Tort-Merino A .Reference: Neuropsychology 2023. -
Diagnostic Performance and Clinical Applicability of Blood-Based Biomarkers in a Prospective Memory Clinic Cohort
Authors: Sarto J, Ruiz-García R, Guillén N, Ramos-Campoy Ó, Falgàs N, Esteller D, Contador J, Fernández G, González Y, Tort-Merino A, Juncà-Parella J, Bosch B, Borrego-Écija S, Molina-Porcel L, Castellví M, Vergara M, Antonell A, Augé JM, Naranjo L, Sanchez-Valle R, Lladó A, Balasa M .Reference: Neurology 2023. -
Temporal order of clinical and biomarker changes in familial frontotemporal dementia
Authors: Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, Forsberg L, Brushaber D, Rojas JC, VandeVrede L, Ljubenkov P, Kramer J, Casaletto KB, Appleby B, Bordelon Y, Botha H, Dickerson BC, Domoto-Reilly K, Fields JA, Foroud T, Gavrilova R, Geschwind D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Hall MGH, Hsiung GY, Huey ED, Irwin D, Jones DT, Kantarci K, Kaufer D, Knopman D, Kremers W, Lago AL, Lapid MI, Litvan I, Lucente D, Mackenzie IR, Mendez MF, Mester C, Miller BL, Onyike CU, Rademakers R, Ramanan VK, Ramos EM, Rao M, Rascovsky K, Rankin KP, Roberson ED, Savica R, Tartaglia MC, Weintraub S, Wong B, Cash DM, Bouzigues A, Swift IJ, Peakman G, Bocchetta M, Todd EG, Convery RS, Rowe JB, Borroni B, Galimberti D, Tiraboschi P, Masellis M, Finger E, van Swieten JC, Seelaar H, Jiskoot LC, Sorbi S, Butler CR, Graff C, Gerhard A, Langheinrich T, Laforce R, Sanchez-Valle R, de Mendonça A, Moreno F, Synofzik M, Vandenberghe R, Ducharme S, Le Ber I, Levin J, Danek A, Otto M, Pasquier F, Santana I, Kornak J, Boeve BF, Rosen HJ, Rohrer JD, Boxer AL, Frontotemporal Dementia Prevention Initiative (FPI) Investigators.Reference: Nature Medicine 2022. -
CSF Biomarkers in COVID-19 Associated Encephalopathy and Encephalitis Predict Long-Term Outcome
Authors: Guasp M, Muñoz-Sánchez G, Martínez-Hernández E, Santana D, Carbayo Á, Naranjo L, Bolós U, Framil M, Saiz A, Balasa M, Ruiz-García R, Sánchez-Valle R, Barcelona Neuro-COVID Study Group.Reference: Frontiers In Immunology 2022. -
Sex differences in early-onset Alzheimer's disease
Authors: Contador J, Pérez-Millan A, Guillén N, Sarto J, Tort-Merino A, Balasa M, Falgàs N, Castellví M, Borrego-Écija S, Juncà-Parella J, Bosch B, Fernández-Villullas G, Ramos-Campoy O, Antonell A, Bargalló N, Sanchez-Valle R, Sala-Llonch R, Lladó A .Reference: European Journal Of Neurology 2022. -
Barcelona scale for buccophonatory apraxia: quantitative assessment tool
Authors: Montagut N, Borrego-Écija S, Herrero J, Lladó A, Balasa M, Muñoz E, Valldeoriola F, Sánchez-Valle R .Reference: Neurologia 2022. -
Synaptic, axonal damage and inflammatory cerebrospinal fluid biomarkers in neurodegenerative dementias
Authors: Antonell A, Tort-Merino A, Ríos J, Balasa M, Borrego-Écija S, Auge JM, Muñoz-García C, Bosch B, Falgàs N, Rami L, Ramos-Campoy O, Blennow K, Zetterberg H, Molinuevo JL, Lladó A, Sánchez-Valle R .Reference: Alzheimers & Dementia 2020.
Featured Projects
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Genetic dementias (genetic Alzheimer’s disease, frontotemporal dementia and prion diseases): longitudinal changes and expression and epigenetic differences with sporadic cases.
Principal investigator: Raquel Sanchez del Valle DíazFunder: ISCII-Subdireccion General de Evaluacion y el Fondo Europeo de Desarrollo Regional (FEDER)Code: PI2000448Duration: 01/01/2021 - 31/12/2023 -
Estudio de biomarcadores y desarrollo de nuevas estrategias terapéuticas en una cohorte multicéntrica de Demencia Frontotemporal.
Principal investigator: Albert Lleo, Gerard Piñol, Raquel Sanchez del Valle DíazDuration: 01/07/2017 - 31/12/2019 -
Study of genetic frontotemporal dementia in preclinical and early stages of the disease: cognitive performance, structural and functional neuroimaging and biochemical markers (GENFI2-Barcelona)
Principal investigator: Raquel Sanchez del Valle DíazCode: TV3-20143810Duration: 20/05/2015 - 19/05/2020 -
Phase II/III Randomized, Double-Blind, Placebo-Controlled Multi-Center Study of 2 Potential Disease Modifying Therapies in Individuals at Risk for and With Dominantly Inherited Alzheimer's Disease
Principal investigator: Raquel Sanchez del Valle DíazDuration: 14/07/2014 -
Alzheimer’s Disease Prediction Service (ADPS): digital biomarker for Real-World Evidence (RWE) in AD
Principal investigator: Raquel Sanchez-ValleCode: EIT Health 18066/2017Duration: 01/01/2018 - 31/12/2018