Search results

• 3. Sudden cardiac death without an apparent cause: post-mortem genetic study

  Our group is part of a collaborative effort between the Institut de Medicina Legal de Catalunya, Hospital Josep Trueta (Girona) and Hospital Sant J...

  Research – Research lines

• 4. International collaboration for genome-wide association studies in Brugada and long QT syndrome

  This international collaboration of >70 centres has allowed the identification of common genetic variants that have a strong impact of the predispo...

  Research – Research lines

• 1. Translational research devoted to genomic profiling, assessing mutations and copy number alterations (panels, exome, and, in some cases, whole genome) of lymphoproliferative disorders

  Directed by Armando López-Guillermo.  Assessment of mutations and copy number alterations (exome and whole genome in some cases) of main lymphomas...

  Research – Research lines

• 2. Translational research devoted to study the cellular microenvironment in FL, CLL and other lymphomas

  Directed by Laura Magnano. Microenvironment has demonstrated to be critical in the development of lymphomas, as well as the prognosis and the resp...

  Research – Research lines

• 3. Epidemiological and prognostic studies based on clinical variables and biomarkers linked to the biology of lymphomas

  Directed by Eva Giné. We have participated in several international initiatives to develop prognostic scores based in both clinical variables and...

  Research – Research lines

• 4. New therapies in lymphoproliferative disorders, including developing and performing clinical trials with experimental targeted therapies

  Directed by Julio Delgado. Clinical research with new drugs from academic and pharma trials. Of note is the use of an academic CD-19 CAR- T cell d...

  Research – Research lines

• 1. Nutrition, obesity, diabetes, and cardiovascular disease: from epidemiology to mechanistic studies

  Dietary habits have strong effects on health. From epidemiological data, we aim to evaluate the impact of whole foods and dietary patterns on the i...

  Research – Research lines

• 2. Detection of atherosclerosis: a road to personalized medicine in dyslipidemia and diabetes

  Carotid and femoral ultrasound examination and plaque detection may help tailor clinical interventions in patients (metabolic syndrome, type 1 and...

  Research – Research lines

• 3. Monogenic forms of diabetes

  Monogenic diabetes represents a heterogeneous group of disorders resulting from defects in single genes. The prevalence of monogenic diabetes is es...

  Research – Research lines

• 4. Impact of bariatric surgery on health

  The health burden of excess body adiposity is well documented. In the context of our extensive bariatric surgery program, we aim to better understa...

  Research – Research lines

• 5. Advanced therapies for type 1 diabetes. The artificial pancreas concept

  Clinical studies have shown that automatic systems (artificial pancreas) can achieve better control of glucose levels than standard treatment in wh...

  Research – Research lines

• 6. Hypoglycemia and its consequences in patients with diabetes

  Hypoglycemia is an important complication of glucose-lowering therapy in patients with diabetes. Attempts made at intensive glycemic control invari...

  Research – Research lines

• 7. Regenerative medicine strategies to treat beta cell deficiency in diabetes

  Diabetes is characterized by an absolute (type 1 diabetes) or relative (type 2 diabetes) deficit in functional beta cell mass. Hence, regeneration...

  Research – Research lines

• 8. Advancing antigen-specific nanomedicines for the treatment of type 1 diabetes

  In collaboration with the group 'Patogènia i tractament de la autoimmunitat' the project involves the development of novel methodologies to identif...

  Research – Research lines

• Colorectal cancer

  Directed by Dr. Joan Maurel To evaluate intrinsic and acquired mechanisms of resistance to chemotherapy and targeted agents in metastatic colore...

  Research – Research lines

• Brain tumors

  Directed by  Dr. Estela Pineda Identification and characterization of new factors involved in NSC maintenance and differentiation, with a specia...

  Research – Research lines

• Melanoma

  Directed by Dr. Ana Arance and Dr. Francisco Aya To identify novel biomarkers predictive of survival and/or treatment response to targeted th...

  Research – Research lines

• Early drug development (Clinical Trial Unit)

  Directed by Aleix Prat To promote and execute phase 1-3 clinical trials. To determine the pharmacodynamics and pharmacokinetics of novel drugs....

  Research – Research lines

• 1. Protective effects of Mediterranean diet

  Protective effects of Mediterranean diet on cardiovascular and cerebrovascular prevention (chronic diseases, neurodegenerative diseases and cancer).

  Research – Research lines

• 2. Protective effects of alcohol (beer or wine)

  Protective effects of alcohol, fermented beverages like beer or wine, consumption on health.

  Research – Research lines