Líneas de investigación

  • Physiology and pathophysiology of pain and chronic itching. Study of the ionic channels involved in neuronal excitability in the sensory nervous system

    Study of the ionic channels that regulate the electrical activity of sensory neurons and how they are altered during the pathology. Identification of new pharmacological targets for neuropathic and inflammatory pain.

  • Traffic and regulation of the channels of K+ and Cl- in cell physiology. Interaction with proteins and membrane lipids

    Mechanisms that regulate the expression and function of ion channels and their participation in mechanisms such as contraction and cellular volume.

  • Ocular physiology: dry eye physiopathology and sensory neurons on the ocular surface. Pathophysiology of the drainage of aqueous humour and the physiopathology of glaucoma

    Study of the ionic channels involved in the detection of painful and irritating stimuli on the ocular surface and its role in eye pathologies such as the dry eye or conjunctivitis. Study of the ionic mechanisms involved in the role of trabecular cells and the regulation of aqueous humour and intraocular pressure in physiological conditions and during glaucoma.

  • Glutamatergic signalling: functional interaction between AMPARs and auxiliary subunits and other proteins that interact with it

    Identification and characterisation of proteins that regulate the expression and composition of glutamatergic receptors and how they determine the function of the glutamate receptor in the synapse.

  • NMDAR receptor pharmacology and function in mutations related to neurological diseases

    Functional studies of NMDAR receptors with new block synthesis compounds and positive allosteric modulators in the framework of neurological diseases.