Epigenómica biomédica

Publicaciones destacadas

Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

Vilarrasa-Blasi R; Soler-Vila P; Verdaguer-Dot N; Russiñol N; Di Stefano M;

(...)

Stunnenberg HG; Gut I; Campo E; Marti-Renom MA; Martin-Subero JI .

Referencia:
Nature Communications 2021.
Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

Speedy HE; Beekman R; Chapaprieta V; Orlando G; Law PJ;

(...)

Allan JM; López-Otín C; Campo E; Houlston RS; Martín-Subero JI .

Referencia:
Nature Communications 2019.
The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

Beekman R; Chapaprieta V; Russiñol N; Vilarrasa-Blasi R; Verdaguer-Dot N;

(...)

López-Otín C; Gut I; Stunnenberg HG; Campo E; Martin-Subero JI .

Referencia:
Nature Medicine 2018.
Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage

Queiros, Ana C.; Beekman, Renee; Vilarrasa-Blasi, Roser; Duran-Ferrer, Marti; Clot, Guillem;

(...)

Heath, Simon; Gut, Ivo G.; Siebert, Reiner; Campo, Elias; Martin-Subero, Jose I.;.

Referencia:
Cancer Cell 2016.
Whole-genome fingerprint of the DNA methylome during human B cell differentiation

Kulis, Marta; Merkel, Angelika; Heath, Simon; Queiros, Ana C.; Schuyler, Ronald P.;

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Siebert, Reiner; Kueppers, Ralf; Gut, Ivo G.; Campo, Elias; Martin-Subero, Jose I.;.

Referencia:
Nature Genetics 2015.
Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers

Agirre, Xabier; Castellano, Giancarlo; Pascual, Marien; Heath, Simon; Kulis, Marta;

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Melnick, Ari; Stunnenberg, Hendrik G.; Gut, Ivo G.; Prosper, Felipe; Martin-Subero, Jose I.;.

Referencia:
Genome Research 2015.
A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact

Queirós A.; Villamor N.; Clot G.; Martinez-Trillos A.; Kulis M.;

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López-Otín C.; Rozman C.; Campo E.; López-Guillermo A.; Martín-Subero J..

Referencia:
Leukemia 2015.
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia

Kulis, Marta; Heath, Simon; Bibikova, Marina; Queiros, Ana C; Navarro, Alba;

(...)

Lopez-Guillermo, Armando; Gut, Ivo; Lopez-Otin, Carlos; Campo, Elias; Martin-Subero, Jose I.

Referencia:
Nature Genetics 2012.