Publicaciones destacadas

  • Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

    Autores: Speedy HE, Beekman R, Chapaprieta V, Orlando G, Law PJ, Martín-García D, Gutiérrez-Abril J, Catovsky D, Beà S, Clot G, Puiggròs M, Torrents D, Puente XS, Allan JM, López-Otín C, Campo E, Houlston RS, Martín-Subero JI.
    Referencia: Nature Communications 2019.
  • Insight into origins, mechanisms & utility of DNA methylation in B cell malignancies.

    Autores: Oakes CC; Martin-Subero JI.
    Referencia: Blood 2018.
  • Charting the dynamic epigenome during B-cell development

    Autores: Martin-Subero J; Oakes C.
    Referencia: Seminars In Cancer Biology 2018.
  • The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

    Autores: Beekman R, Chapaprieta V, Russiñol N, Vilarrasa-Blasi R, Verdaguer-Dot N, Martens JHA, Duran-Ferrer M, Kulis M, Serra F, Javierre BM, Wingett SW, Clot G, Queirós AC, Castellano G, Blanc J, Gut M, Merkel A, Heath S, Vlasova A, Ullrich S, Palumbo E, Enjuanes A, Martín-García D, Beà S, Pinyol M, Aymerich M, Royo R, Puiggros M, Torrents D, Datta A, Lowy E, Kostadima M, Roller M, Clarke L, Flicek P, Agirre X, Prosper F, Baumann T, Delgado J, López-Guillermo A, Fraser P, Yaspo ML, Guigó R, Siebert R, Martí-Renom MA, Puente XS, López-Otín C, Gut I, Stunnenberg HG, Campo E, Martin-Subero JI.
    Referencia: Nature Medicine 2018.
  • Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage

    Autores: Queiros, Ana C.; Beekman, Renee; Vilarrasa-Blasi, Roser; Duran-Ferrer, Marti; Clot, Guillem; Merkel, Angelika; Raineri, Emanuele; Russinol, Nuria; Castellano, Giancarlo; Bea, Silvia; Navarro, Alba; Kulis, Marta; Verdaguer-Dot, Nuria; Jares, Pedro; Enjuanes, Anna; Jose Calasanz, Maria; Bergmann, Anke; Vater, Inga; Salaverria, Itziar; van de Werken, Harmen J. G.; Wilson, Wyndham H.; Datta, Avik; Flicek, Paul; Royo, Romina; Martens, Joost; Gine, Eva; Lopez-Guillermo, Armando; Stunnenberg, Hendrik G.; Klapper, Wolfram; Pott, Christiane; Heath, Simon; Gut, Ivo G.; Siebert, Reiner; Campo, Elias; Martin-Subero, Jose I.;.
    Referencia: Cancer Cell 2016.
  • Non-coding recurrent mutations in chronic lymphocytic leukaemia

    Autores: Puente XS, Beà S, Valdés-Mas R, Villamor N, Gutiérrez-Abril J, Martín-Subero JI, Munar M, Rubio-Pérez C, Jares P, Aymerich M, Baumann T, Beekman R, Belver L, Carrio A, Castellano G, Clot G, Colado E, Colomer D, Costa D, Delgado J, Enjuanes A, Estivill X, Ferrando AA, Gelpí JL, González B, González S, González M, Gut M, Hernández-Rivas JM, López-Guerra M, Martín-García D, Navarro A, Nicolás P, Orozco M, Payer ÁR, Pinyol M, Pisano DG, Puente DA, Queirós AC, Quesada V, Romeo-Casabona CM, Royo C, Royo R, Rozman M, Russiñol N, Salaverría I, Stamatopoulos K, Stunnenberg HG, Tamborero D, Terol MJ, Valencia A, López-Bigas N, Torrents D, Gut I, López-Guillermo A, López-Otín C, Campo E.
    Referencia: Nature 2015.
  • A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact

    Autores: Queirós A., Villamor N., Clot G., Martinez-Trillos A., Kulis M., Navarro A., Penas E., Jayne S., Majid A., Richter J., Bergmann A., Kolarova J., Royo C., Russiñol N., Castellano G., Pinyol M., Bea S., Salaverria I., López-Guerra M., Colomer D., Aymerich M., Rozman M., Delgado J., Giné E., González-Díaz M., Puente X., Siebert R., Dyer M., López-Otín C., Rozman C., Campo E., López-Guillermo A., Martín-Subero J..
    Referencia: Leukemia 2015.
  • Whole-genome fingerprint of the DNA methylome during human B cell differentiation

    Autores: Kulis, Marta; Merkel, Angelika; Heath, Simon; Queiros, Ana C.; Schuyler, Ronald P.; Castellano, Giancarlo; Beekman, Renee; Raineri, Emanuele; Esteve, Anna; Clot, Guillem; Verdaguer-Dot, Nuria; Duran-Ferrer, Marti; Russinol, Nuria; Vilarrasa-Blasi, Roser; Ecker, Simone; Pancaldi, Vera; Rico, Daniel; Agueda, Lidia; Blanc, Julie; Richardson, David; Clarke, Laura; Datta, Avik; Pascual, Marien; Agirre, Xabier; Prosper, Felipe; Alignani, Diego; Paiva, Bruno; Caron, Gersende; Fest, Thierry; Muench, Marcus O.; Fomin, Marina E.; Lee, Seung-Tae; Wiemels, Joseph L.; Valencia, Alfonso; Gut, Marta; Flicek, Paul; Stunnenberg, Hendrik G.; Siebert, Reiner; Kueppers, Ralf; Gut, Ivo G.; Campo, Elias; Martin-Subero, Jose I.;.
    Referencia: Nature Genetics 2015.
  • Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers

    Autores: Agirre, Xabier; Castellano, Giancarlo; Pascual, Marien; Heath, Simon; Kulis, Marta; Segura, Victor; Bergmann, Anke; Esteve, Anna; Merkel, Angelika; Raineri, Emanuele; Agueda, Lidia; Blanc, Julie; Richardson, David; Clarke, Laura; Datta, Avik; Russinol, Nuria; Queiros, Ana C.; Beekman, Renee; Rodriguez-Madoz, Juan R.; San Jose-Eneriz, Edurne; Fang, Fang; Gutierrez, Norma C.; Garcia-Verdugo, Jose M.; Robson, Michael I.; Schirmer, Eric C.; Guruceaga, Elisabeth; Martens, Joost H. A.; Gut, Marta; Calasanz, Maria J.; Flicek, Paul; Siebert, Reiner; Campo, Elias; San Miguel, Jesus F.; Melnick, Ari; Stunnenberg, Hendrik G.; Gut, Ivo G.; Prosper, Felipe; Martin-Subero, Jose I.;.
    Referencia: Genome Research 2015.
  • Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia

    Autores: Kulis, Marta; Heath, Simon; Bibikova, Marina; Queiros, Ana C; Navarro, Alba; Clot, Guillem; Castellano, Giancarlo; Brun-Heath, Isabelle; Pinyol, Magda; Barberan-Soler, Sergio; Papasaikas, Panagiotis; Jares, Pedro; Bea, Silvia; Rico, Daniel; Ecker, Simone; Rubio, Miriam; Royo, Romina; Ho, Vincent; Klotzle, Brandy; Hernandez, Lluis; Conde, Laura; Lopez-Guerra, Monica; Colomer, Dolors; Villamor, Neus; Aymerich, Marta; Rozman, Maria; Bayes, Monica; Gut, Marta; Gelpi, Josep L; Orozco, Modesto; Fan, Jian-Bing; Quesada, Victor; Puente, Xose S; Pisano, David G; Valencia, Alfonso; Lopez-Guillermo, Armando; Gut, Ivo; Lopez-Otin, Carlos; Campo, Elias; Martin-Subero, Jose I.
    Referencia: Nature Genetics 2012.