Líneas de investigación

  • Myeloma and other monoclonal gammapathies

    Multiple myeloma and systemic AL amyloidosis. Minimal residual disease, extramedullary involvement in myeloma, cardiac involvement in amyloidosis, and multicentric clinical trials with novel drugs.

  • Mechanisms of progression in monoclonal gammopathies

    Mechanisms of  progression and control in patients with multiple myeloma. Molecular and cellular features of  patients with long-lasting stable monoclonal gammopathy of undetermined significance and smoldering myeloma. Oligoclonal response and minimal residual disease in myeloma: impact of immune reconstitution and bone marrow microenvironment. Immunotherapy in monoclonal gammopathies. Clinical trials with novel molecules in myeloma and macroglobulinemia.

  • Myeloid neoplasmas

    Natural history and prognosis of chronic myeloid leukemia, myeloproliferative neoplasms, acute myeloid leukemia and myelodysplastic syndromes; prognostic importance of newer molecular markers in these diseases; clinical trials with new drugs.

  • Lymphoid neoplasms

    Lymphomas, chronic lymphocytic leukemia and the other lymphoproliferative disorders:

    Study of progression mechanisms of the disease, genome of CLL and lymphoma, minimum residual disease and biological prognostic models.