Señalización hepatocelular y cáncer

Publicaciones destacadas

Lymphocyte exhaustion in hepatocellular carcinoma: a dynamic evolution across disease stages

Fuster-Anglada, C; Corominas, J; Marsal, A; Llarch, N; Iserte, G;

(...)

Saavedra, C; Reig, M; Boix, L; Marí, M; Díaz, A.

Referencia:
Frontiers In Immunology 2025.
Dynamic changes in immune cell populations by AXL kinase targeting diminish liver inflammation and fibrosis in experimental MASH

Grondal, SM; Tutusaus, A; Boix, L; Reig, M; Blo, M;

(...)

Jackson, A; de Frutos, PG; Lorens, JB; Morales, A; Marí, M.

Referencia:
Frontiers In Immunology 2024.
Induction of the Inflammasome Pathway by Tyrosine Kinase Inhibitors Provides an Actionable Therapeutic Target for Hepatocellular Carcinoma

Tutusaus, A; Sanduzzi-Zamparelli, M; Boix, L; Rider, P; Subías, S;

de Frutos, PG; Colell, A; Marí, M; Reig, M; Morales, A.

Referencia:
Cancers 2024.
Sex-based differences in natural killer T cell-mediated protection against diet-induced steatohepatitis in Balb/c mice

Cuño-Gómiz, C; de Gregorio, E; Tutusaus, A; Rider, P; Andrés-Sánchez, N;

Colell, A; Morales, A; Marí, M.

Referencia:
Biology Of Sex Differences 2023.
Hepatocellular Carcinoma: Molecular Pathogenesis and Therapeutic Advances

Cucarull, B; Tutusaus, A; Rider, P; Hernáez-Alsina, T; Cuño, C;

de Frutos, PG; Colell, A; Marí, M; Morales, A.

Referencia:
Cancers 2022.
Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis

Martínez-Bosch, N; Cristóbal, H; Iglesias, M; Gironella, M; Barranco, L;

(...)

Moreno, M; Morales, A; Guerra, C; Navarro, P; de Frutos, PG.

Referencia:
Ebiomedicine 2022.
Antioxidants Threaten Multikinase Inhibitor Efficacy against Liver Cancer by Blocking Mitochondrial Reactive Oxygen Species

Cucarull, B; Tutusaus, A; Hernáez-Alsina, T; de Frutos, PG; Reig, M;

Colell, A; Marí, M; Morales, A.

Referencia:
Antioxidants 2021.
Growth Arrest-Specific Factor 6 (GAS6) Is Increased in COVID-19 Patients and Predicts Clinical Outcome

Morales, A; Rello, SR; Cristóbal, H; Fiz-López, A; Arribas, E;

(...)

de la Cal-Sabater, P; Nicolaes, GAF; Ortiz-Pérez, JT; Bernardo, D; de Frutos, PG.

Referencia:
Biomedicines 2021.
Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense

Bosch, M; Sánchez-Alvarez, M; Fajardo, A; Kapetanovic, R; Steiner, B;

(...)

Sweet, MJ; Bozza, PT; Gross, SP; Parton, RG; Pol, A.

Referencia:
Science 2020.
Regorafenib Alteration of the BCL-xL/MCL-1 Ratio Provides a Therapeutic Opportunity for BH3-Mimetics in Hepatocellular Carcinoma Models

Cucarull, B; Tutusaus, A; Subías, M; Stefanovic, M; Hernáez-Alsina, T;

(...)

de Frutos, PG; Marí, M; Colell, A; Bruix, J; Morales, A.

Referencia:
Cancers 2020.