Rubén Fernández-Santiago

Sobre mí

Publicaciones destacadas

• SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinson's Disease

  Autores:

  Fernandez-Santiago, Ruben; Martin-Flores, Nuria; Antonelli, Francesca; Cerquera, Catalina; Moreno, Veronica;

  (...)

  Koks, Sulev; Taba, Pille; Hassin-Baer, Sharon; Marti, Maria-Josep; Malagelada, Cristina.

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  Referencia: Movement Disorders 2019.

• Whole-genome DNA hyper-methylation in iPSC-derived dopaminergic neurons from Parkinson's disease patients

  Autores:

  Fernandez-Santiago, Ruben; Merkel, Angelika; Castellano, Giancarlo; Heath, Simon; Raya, Angel;

  Tolosa, Eduard; Marti, Maria-Jose; Consiglio, Antonella; Ezquerra, Mario.

  Referencia: Clinical Epigenetics 2019.

• MicroRNA alterations in iPSC-derived dopaminergic neurons from Parkinson disease patients

  Autores:

  Tolosa, Eduard; Botta-Orfila, Teresa; Morato, Xavier; Calatayud, Carles; Ferrer-Lorente, Raquel;

  (...)

  Gaig, Caries; Raya, Angel; Consiglio, Antonella; Ezquerra, Mario; Fernandez-Santiago, Ruben.

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  Referencia: Neurobiology Of Aging 2018.

• α-synuclein (SNCA) but not dynamin 3 (DNM3) influences age at onset of leucine-rich repeat kinase 2 (LRRK2) Parkinson's disease in Spain

  Autores:

  Fernandez-Santiago, Ruben; Garrido, Alicia; Infante, Jon; Gonzalez-Aramburu, Isabel; Sierra, Maria;

  (...)

  Compta, Yaroslau; Marti, Maria-Jose; Rios, Jose; Tolosa, Eduardo; Ezquerra, Mario.

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  Referencia: Movement Disorders 2018.

• ABSENCE OF LRRK2 MUTATIONS IN A COHORT OF PATIENTS WITH IDIOPATHIC REM SLEEP BEHAVIOR DISORDER

  Autores:

  Fernandez-Santiago, Ruben; Iranzo, Alex; Gaig, Carles; Serradell, Monica; Fernandez, Manel;

  Tolosa, Eduardo; Santamaria, Joan; Ezquerra, Mario.

  Referencia: Neurology 2016.

• The MC1R melanoma risk variant p.R160W is associated with Parkinson disease.

  Autores:

  Tell-Marti, Gemma; Anton Puig-Butille, Joan; Potrony, Miriam; Badenas, Celia; Mila, Montserrat;

  Malvehy, Josep; Jose Marti, Maria; Ezquerra, Mario; Fernandez-Santiago, Ruben; Puig, Susana.

  Referencia: Annals Of Neurology 2015.

• MicroRNA Association with Synucleinopathy Conversion in Rapid Eye Movement Behavior Disorder

  Autores:

  Fernandez-Santiago, Ruben; Iranzo, Alex; Gaig, Carles; Serradell, Monica; Fernandez, Manel;

  Tolosa, Eduardo; Santamaria, Joan; Ezquerra, Mario.

  Referencia: Annals Of Neurology 2015.

Proyectos destacados

• ‘Phospho-proteome analysis of PBMCs in LRRK2 mutation carriers: expansion and validation of findings of the Barcelona LRRK2 Biorepository’ / Parkinson’s Pathway Biomarkers Fall 2020

  Investigador/a principal: Ruben Fernandez Santiago

  Código: MJFF-000858

  Duración: 28/02/2021 - 28/02/2023

• ‘Tackling the epigenetic regulation of a-synuclein in Parkinson disease’ / ISCIII AES-20 Proyectos de Investigación en Salud (FIS)

  Investigador/a principal: Ruben Fernandez Santiago

  Código: PI20/00659

  Duración: 01/01/2021 - 31/12/2023

• 'The beginnings of Parkinson Disease: a study of early disease mechanisms in a humanized in-vitro model'

  Investigador/a principal: Rubén Fernández-Santiago

  Código: SAF2015-73508-JIN

  Duración: 01/01/2016 - 01/01/2019

• ‘MicroRNAs as biomarkers of the prodromal stage of Parkinson disease’

  Investigador/a principal: Mario Ezquerra

  Código: 11159

  Duración: 01/01/2016 - 01/01/2018

• ‘Gene-gene interaction analysis of the mTOR pathway in L-DOPA induced dyskinesia’

  Investigador/a principal: Mario Ezquerra Trabalón

  Código: MJFF_DYSK_2014

  Duración: 01/01/2014 - 01/01/2016