Resultados de búsqueda

• Transcriptional expression profiles involved in molecular mechanisms of carcinogenesis

  We focus mainly on prostate, breast, urologic, skin, gastrointestinal and lung tumors.

  Investigación – Líneas de investigación

• Genetic and epigenetic diagnosis of autoinflammatory disease

  Directed by Dr. Juan Ignacio Arostegui Extending knowledge of genetic diagnostic tools to improve the determination and management of patients wit...

  Investigación – Líneas de investigación

• Molecular determination of the T-cell specific immune response

  Directed by Dr. Europa Azucena González Study of the T-cell specific immune response, based on molecular and especially genetic definition of the...

  Investigación – Líneas de investigación

• Cellular immunotherapy for the treatment of cancer and other immune-mediated diseases

  Directed by Dr. Daniel Benítez Development of mainly cell therapies based primarily on dendritic cells (vaccines ) directly isolated or monocyte-d...

  Investigación – Líneas de investigación

• Molecular and epigenetic mechanisms responsible for the persistent deleterious effects in target tissue exposed to steroidal hormones

  Translational approach in humans and animal models.

  Investigación – Líneas de investigación

• Neural correlates of mood- and anxiety-related disorders

  Directed by Joaquim Raduà We employ several neuroimaging modalities (e.g., structural, DTI, functional connectivity, fMRI) to investigate the brai...

  Investigación – Líneas de investigación

• Development of neuroimaging-based diagnostic and treatment prediction tools

  Directed by Joaquim Raduà We are working on the development and validation of imaging-based machine-learning models to improve the diagnosis and o...

  Investigación – Líneas de investigación

• Evidence-based syntheses in mental health

  Directed by Joaquim Raduà We conduct syntheses (e.g., meta-analyses, mega-analyses and umbrella reviews) of variables and processes involved in me...

  Investigación – Líneas de investigación

• Integrative genetic profile and identification diagnostic markers

  In order to achieve the complete global genetic landscape of these rare tumors we are studying the molecular profile of poorly characterized Non-Ho...

  Investigación – Líneas de investigación

• Study of intratumoral heterogeneity

  Data already obtained in the analysis of pediatric NHL shows the presence of intratumoral heterogeneity that may represent the existence of differe...

  Investigación – Líneas de investigación

• Identification of genetic biomarkers and drug targets

  Our final goal is to identify target genes/pathways that can be useful biomarkers in the management of pediatric NHL. In detail, we aim to identify...

  Investigación – Líneas de investigación

• 1-Cancer Stem Cells and Cell Plasticity in Cancer

  Cell plasticity predisposes cells to malignant transformation. Tumor cells lose their previously normal identity and function and, through a cellul...

  Investigación – Líneas de investigación

• 2-Stem Cells, Cell Differentiation and Tissue Regeneration

  Normal cells and tissues are continuously adapting themselves to exogenous challenges. Stem cell plasticity is central to the adaptation and regene...

  Investigación – Líneas de investigación

• 3-Cell Plasticity in Immune Cells during Inflammation in Tissue Regeneration and Cancer

  Inflammation has positive and negative functions. On the one hand, inflammation is a normal response of the body to infections and injury. The migr...

  Investigación – Líneas de investigación

• 1. Ischemia-reperfusion injury and expanding criteria for liver graft acceptance

  Maintaining the viability of organs from their recovery to transplantation is a key factor for transplant success and graft survival. Organ damage...

  Investigación – Líneas de investigación

• 2. Endoscopic management of biliary complications following liver transplantation

  The study of biliary complications after liver transplantation has high clinical relevance, due it relatively high incidence, complexity of managem...

  Investigación – Líneas de investigación

• 3. Expanding indications for liver transplantation in relation to pre-existing portal vein thrombosis and portal hypertension

  It is widely known that portal vein thrombosis is a serious complication of chronic liver disease, and the prognosis of liver transplantation depen...

  Investigación – Líneas de investigación

• 4. Expanding indications for transplantation for malignant tumors – hilar cholangiocarcinoma and colorectal cancer liver metastases

  The decrease in the number of patients on liver transplant waiting lists due to the advent of effective treatment for hepatitis C virus has generat...

  Investigación – Líneas de investigación

• 5. Alloimmune response, complications associated with immunosupression, and operational tolerance

  Treatment with immunosupression is associated with a series of risks for the transplanted patient, making minimization key to optimizing post-trans...

  Investigación – Líneas de investigación

• 6. Prevention and treatment of cardiovascular risk factors following liver transplantation

  Cardiovascular diseases represent one of the most common causes of long-term morbidity and mortality after liver transplantation. This group focuse...

  Investigación – Líneas de investigación