Resultados de búsqueda

• Anorexia and other eating disorders

  Our group has studied clinical, neuropsychological and brain alterations in adolescents diagnosed with these disorders over the last fifteen years....

  Investigación – Líneas de investigación

• Obsessive-compulsive disorder (OCD) and Tourette syndrome

  We study patients’ neuroimaging and genetic characteristics in order to differentiate endophenotypes and also use machine learning methodology to p...

  Investigación – Líneas de investigación

• Autism spectrum disorders (ASD)

  Our group has published studies on cognitive and neuroimaging abnormalities in ASD children and adolescents and their siblings as well as ongenetic...

  Investigación – Líneas de investigación

• Involvement of p27 (Kip1) in cancer progression

  p27 (Kip1), a classical inhibitor of cyclin dependent kinases, is also a transcriptional regulator. We are analysing the mechanisms by which p27 re...

  Investigación – Líneas de investigación

• Protein kinases in cancer

  Our research focuses on identifying the molecular mechanism by which the CaMK family regulate cell cycle control and stress response. We are actual...

  Investigación – Líneas de investigación

• Myeloma and other monoclonal gammapathies

  Multiple myeloma and systemic AL amyloidosis. Minimal residual disease, extramedullary involvement in myeloma, cardiac involvement in amyloidosis,...

  Investigación – Líneas de investigación

• Mechanisms of progression in monoclonal gammopathies

  Mechanisms of  progression and control in patients with multiple myeloma. Molecular and cellular features of  patients with long-lasting stable mon...

  Investigación – Líneas de investigación

• Myeloid neoplasmas

  Natural history and prognosis of chronic myeloid leukemia, myeloproliferative neoplasms, acute myeloid leukemia and myelodysplastic syndromes; prog...

  Investigación – Líneas de investigación

• Lymphoid neoplasms

  Lymphomas, chronic lymphocytic leukemia and the other lymphoproliferative disorders: Study of progression mechanisms of the disease, genome of CLL...

  Investigación – Líneas de investigación

• 1. Pathogenesis of osteoporosis and fracture development in primary biliary cholangitis and other chronic cholestatic disorders

  Based on our clinical and experimental studies on the development of osteoporosis in primary biliary cholangitis, we have confirmed its high preval...

  Investigación – Líneas de investigación

• 3. Osteoporosis in premenopausal women and in males. Clinical characteristics and mechanisms involved in the development of the disorder

  We have analyzed the factors associated with the development of osteoporosis in men and in premenopausal women. These studies are important because...

  Investigación – Líneas de investigación

• 2. Osteoporosis in liver transplantation

  For years we studied the characteristics of the bone pathology in patients before and after liver transplant. We recently evaluated whether the bon...

  Investigación – Líneas de investigación

• 4. Evaluation of bone remodelling regulators in the pathogenesis of osteoporosis

  We have analyzed the OPG/RANKL system in different conditions: chronic cholestasis and patients with spinal cord injury. We have also analyzed aspe...

  Investigación – Líneas de investigación

• 5. Biomarkers in Paget disease

  For years we have studied the effectiveness of the use of bone turnover markers to analyze the activity of Paget's bone disease. We recently extend...

  Investigación – Líneas de investigación

• Lung development and ageing as key pathogenic determinants of adulthood respiratory diseases

  Co-directed by Dr. Alvar Agusti and Rosa Faner  We aim to understand the different respiratory diseases from a life-long perspective (Agusti, Fane...

  Investigación – Líneas de investigación

• Chronic Obstructive pulmonary disease (COPD) clinical complexity and heterogeneity

  Directed by Dr. Alvar Agusti   The evidence that COPD may originate early in life opens new opportunities for prediction, prevention, personalised...

  Investigación – Líneas de investigación

• Follicular lymphoma crosstalk with its immune microenvironment as a source novel targeted therapy

  Immune microenvironment is fundamental for Follicular lymphoma (FL) onset and progression. Thus, we study how FL cells shape their microenvironment...

  Investigación – Líneas de investigación

• Novel immunotherapeutic approaches in Non-Hodgkin Lymphoma (NHL)

  20 years ago, rituximab, the first anti-CD20 antibody, revolutionized the immunotherapy for treatment of lymphoma. More recently, subsequent lympho...

  Investigación – Líneas de investigación

• 3D lymphoma patient derived primary cultures: a superior in vitro system for personalized medicine

  In order to obtain meaningful in vitro results and increase the success of bench-to-bedside translation, robust, reliable and reproducible in vitro...

  Investigación – Líneas de investigación

• Functional characterization of oncogenic mechanisms in lymphomagenesis

  The objective of the group is to identify and characterize the functional role of new candidates and signaling pathways, in both cancerous and norm...

  Investigación – Líneas de investigación