Resultados de búsqueda

• Analysis of the influence of the microbiota in skin cancer

   Evaluation of the role of the gut microbiome in the modulation of immunotherapy response and melanoma outcome.

  Investigación – Líneas de investigación

• Identification of biomarkers for melanoma

  Study of circulating free DNA (cfDNA) as a biomarker for melanoma surveillance. Study of circulating melanoma cells (CMC) and single cell sequencing.

  Investigación – Líneas de investigación

• Development of new treatment strategies for melanoma and other skin tumors

  Research in the dermatological implications of targeted therapies in melanoma. Immunotherapy in melanoma and non-melanoma skin cancer. Development...

  Investigación – Líneas de investigación

• Study of the mechanisms involved in carcinogenesis and photocarcinogenesis in melanoma and non-melanoma skin cancer

  Analysis of topical and oral photoprotection. Study of UV effect in skin and melanocytic nevi using imaging techniques and high-throughput molecula...

  Investigación – Líneas de investigación

• Functional validation of paternally-derived embryo proteins during early embryogenesis

  The goal of this line emerges from the recent results derived from the integrative analysis of the proteome and transcriptome from human sperm, ooc...

  Investigación – Líneas de investigación

• Characterization of exosomes isolated from seminal fluid and development of clinically relevant diagnostic and prognostic biomarkers

  Exosomes contained in the seminal fluid may contribute proteins and RNAs to the sperm. Our first goal is to characterize the protein and RNA conten...

  Investigación – Líneas de investigación

• Characterization of epigenetic signatures in the sperm chromatin

  We have identified a non-random distribution of proteins and genes along the sperm chromatin domains which may represent epigenetic marks involved...

  Investigación – Líneas de investigación

• Molecular alterations in semen from couples with idiopathic infertility

  Molecular alterations at the transcriptiomic and proteomic level are analyzed in sperm and seminal plasma from couples with idiopathic infertility...

  Investigación – Líneas de investigación

• Genetics of endocrine disorders

  We are  studying the genetic aspects of hereditary endocrine disorders (multiple endocrine neoplasia, congenital adrenal hyperplasia and monogenic...

  Investigación – Líneas de investigación

• Characterization of genes involved in the familial non-syndromic differentiated thyroid carcinoma

  Differentiated familial thyroid carcinoma represents 3-9% of thyroid carcinomas. Today, the genes involved in some rare syndromic forms in which th...

  Investigación – Líneas de investigación

• Mechanisms involved in redifferentiation of cancer cells

  Oncogenesis is essentially a cell dedifferentiation process. Molecules that induce  cell differentiation, such as retinoic acid, have been used for...

  Investigación – Líneas de investigación

• Addictions in patients with high complexity

   We focus on comorbidity (PTSD, liver disease, depression, cognitive impairment, etc.), care integration, and the reduction of health and social in...

  Investigación – Líneas de investigación

• Ischemic stroke

  Directed by Ángel Chamorro Our research focuses on cerebral microcirculation, particularly microvascular reperfusion failure (no-reflow” phenomeno...

  Investigación – Líneas de investigación

• The immune system in stroke

  Directed by Anna M. Planas We study immune responses after stroke, from local brain reactions to systemic effects in peripheral organs. Our work f...

  Investigación – Líneas de investigación

• Brain hemorrhage

  Directed by Sergi Amaro This line investigates hemorrhagic stroke, including subarachnoid hemorrhage and intracerebral hemorrhage. Research integr...

  Investigación – Líneas de investigación

• Lipids as intracelular messengers in disease

  Directed by Jose Carlos Fernández-Checa Lipids act as structural molecules, energy sources and signalling factors. Our work has focused on lipid i...

  Investigación – Líneas de investigación

• Lipid cell biology and its impact on metabolic liver disease

  Directed by Carmen Garcia-Ruiz The team research efforts aim to understand the homeostasis and trafficking of cholesterol and sphingolipids in the...

  Investigación – Líneas de investigación

• Molecular targets of cancer

  Directed by Pilar Navarro Our research focuses on the molecular mechanisms driving tumor progression, with emphasis on pancreatic cancer, tumor-st...

  Investigación – Líneas de investigación

• Tissue remodeling, fibrosis and cancer

  Directed by Anna Moles Our research investigates tissue remodeling during the onset, progression, and resolution of chronic diseases, with a focus...

  Investigación – Líneas de investigación

• Inflammasome activation and mitochondrial stress in the progression of MAFLD to hepatocellular carcinoma and DILI

  Directed by Sandra Torres We study the progression of MAFLD to hepatocellular carcinoma and drug-induced liver injury (DILI), with special attenti...

  Investigación – Líneas de investigación