Resultados de búsqueda

• 2. Epidemiology and diagnosis of community-acquired pneumonia

  Multicenter studies in the setting of community-acquired pneumonia. New methods for fast diagnosis. New treatments. Resistances of microorganisms....

  Investigación – Líneas de investigación

• 3. Etiopathogenesis, bronchial infection and inflammation in the patient with chronic obstructive pulmonary disease (COPD

  Role of infections in exacerbation of the disease. Study of bronchial and associated systemic response. Analysis of the risk and prognostic factors...

  Investigación – Líneas de investigación

• 4. Chronic pulmonary infections

  Bronchiectasis not associated with cystic fibrosis, immune deficiencies and cystic fibrosis in the adult. Control of bronchial colonization. Study...

  Investigación – Líneas de investigación

• 5. Infectious lung complications in immune depressed patients

  Evaluation of the etiological factors. Optimization of the diagnostic techniques. Study of bronchial inflammatory and associated systemic response....

  Investigación – Líneas de investigación

• 6. Invasive and noninvasive mechanical ventilation

  Epidemiology, costeffectiveness and physiopathology. New techniques. Weaning from mechanical ventilation: role of the inflammatory response and res...

  Investigación – Líneas de investigación

• 7. Porcine model of acute pulmonary damage due to methicillinresistant P. aeruginosa, S. aureus and S. pneumoniae

  Study of new coadjuvant drugs, antibiotics and therapies for pneumonia, prevention of ventilator-associated pneumonia (VAP), and new forms of mecha...

  Investigación – Líneas de investigación

• 8. Translational research laboratory for the microbiology diagnosis and pathogen-host response in respiratory infections

  Respiratory microbiome, advanced and rapid microbiology diagnostic, biofilm associated acute and chronic respiratory infections, advanced imaging i...

  Investigación – Líneas de investigación

• 9. Chronic sleep apnea

  Chronic sleep apnea models Multicenter Study to assess the effect of CPAP on cardiovascular diseases in patients with sleep apnea Telematic c...

  Investigación – Líneas de investigación

• Systemic lupus erythematosus, antiphospholipid syndrome and systemic sclerosis

  Epidemiological multicenter studies on the clinical manifestations and long-term evolution of these diseases Clinical trials in new biological t...

  Investigación – Líneas de investigación

• Sjögren’s syndrome, autoimmune manifestations of hepatitis C virus infection and biological therapies

  Epidemiological multicenter studies on the clinical manifestations and long-term evolution of these diseases Study of IgG4 disease associated wi...

  Investigación – Líneas de investigación

• 1. CAR-T and CAR-NK therapy for the treatment of hematological malignancies

  Directed by Álvaro Urbano Preclinical development of CARs for the treatment of malignant diseases. Specifically, we have developed a CAR against B...

  Investigación – Líneas de investigación

• The neural circuitry of expectation during decision making tasks

  In this project, funded by the European Research Council (ERC-2015-CoG - 683209_PRIORS), we aim to characterize the neural basis of expectation, an...

  Investigación – Líneas de investigación

• The dynamics of sensory evidence integration during perceptual decision making

  During perceptual discrimination task sensory information must be transformed into decision evidence and then temporally integrated in order to yie...

  Investigación – Líneas de investigación

• The neural circuitry of Working Memory (WM): memory interference and disease-mediated deficits

  Working memory is the cognitive function describing the maintenance and processing of information in the brain during brief periods of time. The br...

  Investigación – Líneas de investigación

• 2. CAR-T cell therapies for solid tumours

  Directed by Álvaro Urbano We are developing novel CAR-T cell therapies for the treatment of solid tumours, with a primary focus on breast and ovar...

  Investigación – Líneas de investigación

• 3. Mechanisms of antitumor cytotoxicity of immune cells (NK and T lymphocytes)

  Directed by Álvaro Urbano We use both NK cells and CAR-NK cells to increase the activity of CART cells avoiding CART cell exhaustion and increasin...

  Investigación – Líneas de investigación

• 4. Allogeneic stem cell transplantation: graft versus host disease (GVHD) and Infectious complications

  Directed by Álvaro Urbano GVHD and Infectious complications are the main problems occurring after allogeneic stem cell transplantation, being resp...

  Investigación – Líneas de investigación

• Study of the molecular mechanisms involved in the development of bleeding and thrombotic disorders

  Our group’s scientific trajectory is focused on the study of the mechanisms involved in the development of haemorrhagic pathologies, particularly t...

  Investigación – Líneas de investigación

• Characterization of endothelial dysfunction in association with different pathological situations

  Some diseases have a high cardiovascular risk, such as chronic kidney failure, diabetes, and obesity, among others, in which we surmise that endoth...

  Investigación – Líneas de investigación

• Search for biomarkers of graft-versus-host disease (GvHD)

  We have identified certain endothelial damage in the context of transplanted haematopoietic progenitor cells in patients. The behaviour of these ma...

  Investigación – Líneas de investigación