Resultados de búsqueda

• Patient-derived and genetically engineered models

  We create patient-derived organoids, xenografts (PDXs), and genetically engineered mouse models that replicate the heterogeneity of upper GI tumors...

  Investigación – Líneas de investigación

• Upper GI cancer cell and stromal interactions

  We investigate how interactions among tumor cells, the immune system, and stromal components affect tumor progression and therapy resistance. Under...

  Investigación – Líneas de investigación

• Unravelling the role of lipid droplets in epithelial regeneration and infections

  Directed by Albert Herms  Lipid droplets are very well characterized in liver, muscle or adipose tissue, but little is known about their role in e...

  Investigación – Líneas de investigación

• Understanding mutant selection and early tumorigenesis in ageing epithelia

  Directed by Albert Herms  Epithelial tissues accumulate mutations as we age. We are applying mouse and human epithelioids, advanced primary self-m...

  Investigación – Líneas de investigación

• Neural correlates of aversive and appetitive learning

  Directed by Miquel A. Fullana We study the neurobiology of aversive and appetitive learning, primarily using fMRI. These processes have strong tra...

  Investigación – Líneas de investigación

• Asymptomatic monoclonal gammopathies, extramedullary involvement in multiple myeloma, real-world outcomes and clinical trials

  Directed by Laura Rosiñol Dachs Clinical and biological characterization of asymptomatic gammopathies and their progression, study of extramedulla...

  Investigación – Líneas de investigación

• CAR-T cells against BCMA in multiple myeloma: prognostic factors and development of new chimeric receptors

  Directed by Luis Gerardo Rodríguez CAR-T therapy uses autologous T cells genetically modified. Despite efficacy, relapses occur and questions rema...

  Investigación – Líneas de investigación

• Cardiac involvement and targeted treatments in amyloidosis

  Directed by Carlos Fernández de Larrea Cardiac involvement is the main prognostic marker in AL amyloidosis. We assess the impact of combined strat...

  Investigación – Líneas de investigación

• Advancing therapeutic targets & clinical trials

  Through the previous research line of our experimental lab, our outpatients’ clinic, and our clinical trials team, we participate in the most innov...

  Investigación – Líneas de investigación

• Innovation in oncologic surgery and robotic pancreatic surgery

  Directed by Dr. Fabio Ausania  This line is centered on the NOVELLA project, integrating haemodynamic modelling (CFD/AI), preoperative imaging and...

  Investigación – Líneas de investigación

• DYRK kinases: regulation and role in pancreatic cancer and other human disorders

  Directed by Dr. Susana de la Luna  Protein kinases are central to all cellular processes in eukaryotes and often linked to disease when altered. T...

  Investigación – Líneas de investigación

• 5. Frailty in Hematopoietic Cell Transplant Candidates

  Directed by Mª Queralt Salas Our research studies the incidence, risk factors, and impact of frailty in adult candidates for allogeneic and autolo...

  Investigación – Líneas de investigación

• Antibody–Innate Immune Interactions in Autoimmune Neurological Disorders

  The group investigates the immune mechanisms underlying autoimmune neurological disorders mediated by antibodies against neuronal and glial surface...

  Investigación – Líneas de investigación

• Viral Triggers of Post-Infectious Brain Autoimmunity

  This research axis investigates how viral infections precipitate antibody-mediated autoimmune neurological disorders, using herpes simplex virus ty...

  Investigación – Líneas de investigación

• Antibody Correlates Of Protection In Infectious Brain Disorders To Guide Next-Generation Vaccines

  This research axis focuses on identifying antibody correlates of protection and pathogenicity in neuroinfectious and neuroinflammatory disorders. P...

  Investigación – Líneas de investigación

• Frailty & Sarcopenia in Liver Diseases Hepatic Encephalopathy

  Directed by Anna Baiges Aznar Her research focus on developing new therapies for hepatic encephalopathy and how functional status and physiologic...

  Investigación – Líneas de investigación

• Critical management of patients with Liver Disease

  Directed by Enric Reverter Segura Research focused on improving the management and outcomes of critically ill patients with advanced liver disease...

  Investigación – Líneas de investigación

• Molecular mechanisms of endolysosomal homeostasis and extracellular vesicles.

  Directed by Albert Lu The endolysosomal compartment is central to metabolic and signaling control. It is also the site where exosomes form and are...

  Investigación – Líneas de investigación

• Programa de autoinmunidad sináptica en neurología, psiquiatría y neurociencia cognitiva

  Investigación – Áreas y Programas de Investigación

• Programa de investigación traslacional en cáncer

  Investigación – Áreas y Programas de Investigación