Resultados de búsqueda

• Bone and joint infections

  European Register of Infections/AIDS on joint prostheses, aimed at studying diagnostic methods and the efficacy of new antibiotics in this type of...

  Investigación – Líneas de investigación

• Intestinal microbiota

  We are developing a system to make it possible to perform fecal transplants from healthy volunteers to patients with Clostridium difficile and whic...

  Investigación – Líneas de investigación

• Characterization of the functional impact of driver mutations and the analysis of new potential therapeutic approaches

  Genetic studies have led to the identification of novel recurrent somatic mutations with predicted functional impact, offering new potential therap...

  Investigación – Líneas de investigación

• Development of predictive models recapitulating tumor heterogeneity and their impact on disease evolution, therapy resistance and susceptibility to novel targeted therapies

  Due to the high heterogeneity and complexity of B lymphoid malignancies, the analysis of the effect of novel targeted drugs in different mutational...

  Investigación – Líneas de investigación

• Mechanisms of resistance to targeted therapy

  Treatment with novel targeted drugs like the Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib or the Bcl-2 antagonist venetoclax improved outcome...

  Investigación – Líneas de investigación

• Prevention and treatment of chronic liver diseases

  Directed by Pere Ginès This line focuses on risk factors and early diagnosis of chronic liver diseases in the general population. It defines liver...

  Investigación – Líneas de investigación

• Pathogenic mechanisms of alcohol-related liver disease, effects of abstinence, and novel therapies

  Directed by Elisa Pose This established line combines clinical and translational research on alcohol-related liver disease. It includes independen...

  Investigación – Líneas de investigación

• Mechanisms of disease progression and risk stratification in metabolic dysfunction-associated steatotic liver disease

  Directed by Isabel Graupera This line studies how metabolic dysfunction drives MASLD progression and supports risk stratification for personalized...

  Investigación – Líneas de investigación

• Translational liver cell biology and disease mechanisms in chronic liver disease

  Directed by Mar Coll This translational line focuses on liver inflammation and cellular mechanisms underlying chronic liver disease progression. I...

  Investigación – Líneas de investigación

• Sleep and sleep disorders

  A clinical and electrophysiological assessment of normal sleep in humans and of sleep disorders including the anti-IgLON5 disease, REM sleep behavi...

  Investigación – Líneas de investigación

• Epilepsy

  Characterization of the epileptogenic activity and the surgical and medical therapy of the refractory epilepsy using functional MRI, video-EEG and...

  Investigación – Líneas de investigación

• Neuropathic pain

  Electrophysiological evaluation of the neuropathic pain using nocioceptive evoked potentials and other tools including the startle reaction.

  Investigación – Líneas de investigación

• Motor control

  Assesment of the motor control in healthy subjects and in patients with neurological diseases using acoustic and somatosensorial stimul and prepulse.

  Investigación – Líneas de investigación

• Precision screening, diagnosis, and staging for enhanced liver cancer outcomes

  Directed by Maria Reig  Effective stratification of patients according to their cancer risk is essential to ensure cost-effective screening progra...

  Investigación – Líneas de investigación

• Non-invasive prognostic assessment by radiology in liver cancer

  Directed by Jordi Rimola   It is necessary to identify the radiological imaging biomarkers that have the potential to provide valuable prognostic...

  Investigación – Líneas de investigación

• Predictive factors of treatment response in liver cancer

  Directed by Maria Reig  This research line focuses on identifying and understanding key predictive factors that influence the response to surgical...

  Investigación – Líneas de investigación

• Nanomedicine, cell therapy, and tissue engineering in liver diseases

  Directed by Pedro Melgar-Lesmes We investigate molecular targets in each hepatic cellular compartment involved in liver disease pathophysiology to...

  Investigación – Líneas de investigación

• Multi-omics research in newborn screening, diagnosis, and treatment of rare diseases

  Directed by Judit García-Villoria Translational research in rare diseases, particularly inherited metabolic disorders, based on multi-omics strate...

  Investigación – Líneas de investigación

• Translational application of nanozymes in liver and metabolic diseases

  Directed by Gregori Casals Mercadal We investigate the translational application of cerium- and gold-based nanoenzymes in steatotic liver disease...

  Investigación – Líneas de investigación

• Research and validation of non-invasive biomarkers and antifibrotic strategies

  Directed by Manuel Morales-Ruiz This line centers on the research and clinical validation of non-invasive serological markers for liver injury and...

  Investigación – Líneas de investigación