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• Molecular characterization of human NASH-HCC

  We have molecularly characterized human NASH-HCC at the genomic and molecular levels (Pinyol Journal of Hepatology 2021). 

  Investigación – Líneas de investigación

• Identification of drivers of oncogenesis as targets for therapies in HCC

  Several studies led to the identification of Akt/mTOR pathway [Villanueva Gastroenterology, 2008), EGFR pathway (Keng, Nature Biotech 2009), IGF pa...

  Investigación – Líneas de investigación

• Establishment of a molecular diagnosis and classification of HCC

  Gene-set (three genes) based diagnosis of HCC reported in Llovet, Gastroenterology 2006, and included in EASL-EORTC guidelines. In addition, we pro...

  Investigación – Líneas de investigación

• Molecular characterization and identification of drivers of oncogenesis in cholangiocarcinoma

  We have contributed to the molecular classification of iCCA (Sia, Gastroenterology 2013) and eCCA (Montal, Journal of Hepatology 2020).  We identi...

  Investigación – Líneas de investigación

• Establishment of sorafenib, regorafenib and ramucirumab as standard of care in patients with advanced HCC

  The international RCT showing survival benefits for sorafenib vs placebo, presented at plenary session in ASCO (Llovet, New Engl J Med 2008) was a...

  Investigación – Líneas de investigación

• Cannabis and risky use

  We explore patterns of consumption, health risks and health-literacy, and the development of standardized measures to assess exposure, literacy, an...

  Investigación – Líneas de investigación

• Addictions, lifestyles, and public health

  We address population-level determinants, prevention strategies with an integrated approach (i.e. alongside physical activity, diet or other risk f...

  Investigación – Líneas de investigación

• Digital health and addictions

  Digital health constitutes a cross‑cutting research axis through which we leverage digital tools to enhance prevention, early identification, acces...

  Investigación – Líneas de investigación

• Genomic alterations in aggressive large B-cell lymphoma

  Directed by Silvia Beà To comprehensively characterize the genetic and molecular profiles of aggressive B-cell lymphomas in order to identify accu...

  Investigación – Líneas de investigación

• Head Neck Tumors

  Directed by Dr. Isabel Vilaseca, Dr. F. Xavier Avilés and Dr. Neus Basté Multiomic characterisation of head and neck cancer and its impact in a...

  Investigación – Líneas de investigación

• CAF Plasticity and Heterogeneity in desmoplastic tumors

  We are interested in deciphering and dissecting the plasticity and heterogeneity of cancer-associated fibroblasrs (CAF) during cholangiocarcinogene...

  Investigación – Líneas de investigación

• Cancer Stem Cells in intrahepatic cholangiocarcinoma

  Combining in vitro and in vivo systems with high throughput transcriptomics and bioinformatics, we aim to elucidate the functional role of cancer s...

  Investigación – Líneas de investigación

• Tracing Intra-Tumoral Heterogenenity

  Tumors are highly heterogeneous entities, and we are interested in investigating the interactions between heterogeneous cancer cells and the tumor...

  Investigación – Líneas de investigación

• Thoracic oncology and environmental-related cancer

  Directed by Dr. Laura Mezquita Circulating and tissue biomarkers for immunotherapy in lung cancer Molecular characterization of lung cancer and...

  Investigación – Líneas de investigación

• Characterization and management of hereditary and familial forms of colorectal cancer

  Directed by Francesc Balaguer Dr. Balaguer's research focuses on the clinical and endoscopic characterization of hereditary and familial forms of...

  Investigación – Líneas de investigación

• Colorectal cancer screening

  Directed by Antoni Castells Dr. Castells’ research focuses on the evaluation of population-based strategies, assessment of risk factors to advance...

  Investigación – Líneas de investigación

• Endoscopy for prevention and treatment of colorectal cancer

  Directed by Dr. Maria Pellisé Dr. Pellisé’s research focuses on the implementation of key performance measures and new technologies for improving...

  Investigación – Líneas de investigación

• Innovation and new technologies in gastrointestinal endoscopy

  Directed by Glòria Fernández-Esparrach Dr. Fernández-Esparrach’s research focuses on the development and evaluation of new technologies to improve...

  Investigación – Líneas de investigación

• Physiopathology of pancreatic cancer

  Directed by Dr. Eva Vaquero Dr. Vaquero’s research focuses on the study of pancreatic stellate cells as therapeutic target in pancreatic cancer. B...

  Investigación – Líneas de investigación