Featured publications

• Fasting-Induced Hepatic Gluconeogenesis Is Compromised In Anxa6-/- Mice.

  Alvarez-Guaita A; Bernaus-Esqué M; Blanco-Muñoz P; Liu Y; Sebastian D;

  (...)

  Zorzano A; Tebar F; Enrich C; Grewal T; Rentero C.

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  Reference:

  JOURNAL OF CELLULAR PHYSIOLOGY 2025.

• HRK downregulation and augmented BCL-xL binding to BAK confer apoptotic protection to therapy-induced senescent melanoma cells

  Alcon, Clara; Kovatcheva, Marta; Morales-Sanchez, Paula; Lopez-Polo, Vanessa; Torres, Teresa;

  (...)

  Lu, Albert; Samitier, Josep; Enrich, Carlos; Serrano, Manuel; Montero, Joan.

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  Reference:

  CELL DEATH AND DIFFERENTIATION 2025.

• Novel selective strategies targeting the BCL-2 family to enhance clinical efficacy in ALK-rearranged non-small cell lung cancer

  Martín, F; Alcon, C; Marín, E; Morales-Sánchez, P; Manzano-Muñoz, A;

  (...)

  Lu, A; Villanueva, A; Reguart, N; Teixido, C; Montero, J.

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  Reference:

  Cell Death & Disease 2025.

• Microfluidic-based dynamic BH3 profiling predicts anticancer treatment efficacy

  Manzano-Munoz, Albert; Yeste, Jose; Ortega, Maria A; Martin, Fernando; Lopez, Anna;

  (...)

  Castro, Sandra; Serrano, Cesar; Samitier, Josep; Ramon-Azcon, Javier; Montero, Joan.

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  Reference:

  npj Precision Oncology 2022.

• Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds

  Pallara, C; Cabot, D; Rivas, J; Brun, S; Seco, J;

  Abuasaker, B; Tarragó, T; Jaumot, M; Prades, R; Agell, N.

  Reference:

  Scientific Reports 2022.

• Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions

  Jose, J; Hoque, M; Engel, J; Beevi, SS; Wahba, M;

  (...)

  Timpson, P; Rye, KA; Enrich, C; Rentero, C; Grewal, T.

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  Reference:

  Scientific Reports 2022.

• CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export

  Lu, A; Hsieh, F; Sharma, BR; Vaughn, SR; Enrich, C;

  Pfeffer, SR.

  Reference:

  JOURNAL OF CELL BIOLOGY 2022.

• KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer

  Cabot, D; Brun, S; Paco, N; Ginesta, MM; Gendrau-Sanclemente, N;

  (...)

  Pons, G; Estanyol, JM; Capellà, G; Jaumot, M; Agell, N.

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  Reference:

  ONCOGENE 2021.

• Lack of Annexin A6 exacerbates liver dysfunction and reduces lifespan of NPC1-deficient mice

  Meneses-Salas, E; Garcia-Forn, M; Castany-Pladevall, C; Lu, A; Fajardo, A;

  (...)

  Zanlungo, S; Pérez-Navarro, E; Grewal, T; Enrich, C; Rentero, C.

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  Reference:

  AMERICAN JOURNAL OF PATHOLOGY 2021.

• Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability

  Almacellas, Eugenia; Pelletier, Joffrey; Day, Charles; Ambrosio, Santiago; Tauler, Albert;

  Mauvezin, Caroline.

  Reference:

  Autophagy 2021.