Featured publications

• Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds

  Pallara, C; Cabot, D; Rivas, J; Brun, S; Seco, J;

  Abuasaker, B; Tarragó, T; Jaumot, M; Prades, R; Agell, N.

  Reference:

  Scientific Reports 2022.

• Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions

  Jose, J; Hoque, M; Engel, J; Beevi, SS; Wahba, M;

  (...)

  Timpson, P; Rye, KA; Enrich, C; Rentero, C; Grewal, T.

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  Reference:

  Scientific Reports 2022.

• CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export

  Lu, A; Hsieh, F; Sharma, BR; Vaughn, SR; Enrich, C;

  Pfeffer, SR.

  Reference:

  Journal Of Cell Biology 2022.

• KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer

  Cabot, D; Brun, S; Paco, N; Ginesta, MM; Gendrau-Sanclemente, N;

  (...)

  Pons, G; Estanyol, JM; Capellà, G; Jaumot, M; Agell, N.

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  Reference:

  Oncogene 2021.

• Lack of Annexin A6 exacerbates liver dysfunction and reduces lifespan of NPC1-deficient mice

  Meneses-Salas, E; Garcia-Forn, M; Castany-Pladevall, C; Lu, A; Fajardo, A;

  (...)

  Zanlungo, S; Pérez-Navarro, E; Grewal, T; Enrich, C; Rentero, C.

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  Reference:

  American Journal Of Pathology 2021.

• Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability

  Almacellas, Eugenia; Pelletier, Joffrey; Day, Charles; Ambrosio, Santiago; Tauler, Albert;

  Mauvezin, Caroline.

  Reference:

  Autophagy 2021.

• Annexin A6 is critical to maintain glucose homeostasis and survival during liver regeneration

  Alvarez-Guaita, A; Blanco-Muñoz, P; Meneses-Salas, E; Wahba, M; Pollock, AH;

  (...)

  Tebar, F; Moss, SE; Grewal, T; Enrich, C; Rentero, C.

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  Reference:

  Hepatology 2020.

• Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells

  Meneses-Salas, E; Garcia-Melero, A; Kanerva, K; Blanco-Munoz, P; Morales-Paytuvi, F;

  (...)

  Tebar, F; Ikonen, E; Grewal, T; Enrich, C; Rentero, C.

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  Reference:

  Cellular And Molecular Life Sciences 2020.

• Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse

  Ercilla A; Feu S; Aranda S; Llopis A; Brynjólfsdóttir SH;

  Sørensen CS; Toledo LI; Agell N.

  Reference:

  Cellular And Molecular Life Sciences 2020.