Transducción de señales, compartimentos intracelulares y cáncer

Publicaciones destacadas

Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds

Pallara, C; Cabot, D; Rivas, J; Brun, S; Seco, J;

Abuasaker, B; Tarragó, T; Jaumot, M; Prades, R; Agell, N.

Referencia:
Scientific Reports 2022.
Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions

Jose, J; Hoque, M; Engel, J; Beevi, SS; Wahba, M;

(...)

Timpson, P; Rye, KA; Enrich, C; Rentero, C; Grewal, T.

Referencia:
Scientific Reports 2022.
CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export

Lu, A; Hsieh, F; Sharma, BR; Vaughn, SR; Enrich, C;

Pfeffer, SR.

Referencia:
Journal Of Cell Biology 2022.
KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer

Cabot, Debora; Brun, Sonia; Paco, Noelia; Ginesta, Mireia M; Gendrau-Sanclemente, Nuria;

(...)

Pons, Gabriel; Estanyol, Josep M; Capella, Gabriel; Jaumot, Montserrat; Agell, Neus.

Referencia:
Oncogene 2021.
Lack of Annexin A6 exacerbates liver dysfunction and reduces lifespan of NPC1-deficient mice

Meneses-Salas, Elsa; Garcia-Forn, Marta; Castany-Pladevall, Carla; Lu, Albert; Fajardo, Alba;

(...)

Zanlungo, Silvana; Perez-Navarro, Esther; Grewal, Thomas; Enrich, Carlos; Rentero, Carles.

Referencia:
American Journal Of Pathology 2021.
Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability

Almacellas, Eugenia; Pelletier, Joffrey; Day, Charles; Ambrosio, Santiago; Tauler, Albert;

Mauvezin, Caroline.

Referencia:
Autophagy 2021.
Annexin A6 is critical to maintain glucose homeostasis and survival during liver regeneration

Alvarez-Guaita, Anna; Blanco-Munoz, Patricia; Meneses-Salas, Elsa; Wahba, Mohamed; Pollock, Abigail H;

(...)

Tebar, Francesc; Moss, Stephen E; Grewal, Thomas; Enrich, Carlos; Rentero, Carles.

Referencia:
Hepatology 2020.
Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells

Meneses-Salas, Elsa; Garcia-Melero, Ana; Kanerva, Kristiina; Blanco-Munoz, Patricia; Morales-Paytuvi, Frederic;

(...)

Tebar, Francesc; Ikonen, Elina; Grewal, Thomas; Enrich, Carlos; Rentero, Carles.

Referencia:
Cellular And Molecular Life Sciences 2020.
Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse

Ercilla A; Feu S; Aranda S; Llopis A; Brynjólfsdóttir SH;

Sørensen CS; Toledo LI; Agell N.

Referencia:
Cellular And Molecular Life Sciences 2020.