Featured publications

• Comparative genomic landscape of acquired resistance in pancreatic cancer treated with pan-RAS or KRASG12C inhibitors.

  Castet F; Tian TV; Macarulla T;

  Reference:

  Annals Of Oncology 2025.

• A Phase II Trial to Assess the Evolution of the KRAS Mutation Load by Liquid Biopsy in Patients With Resectable Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant NALIRIFOX.

  Álvarez-Gallego R; Macarulla T; Laquente B; Peinado P; Castet F;

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  Sanz-García E; Toledano C; Quijano Y; Vicente E; Cubillo A.

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  Reference:

  American Journal Of Clinical Oncology-Cancer Clinical Trials 2025.

• Tumor Treating Fields With Gemcitabine and Nab-Paclitaxel for Locally Advanced Pancreatic Adenocarcinoma: Randomized, Open-Label, Pivotal Phase III PANOVA-3 Study

  Babiker, Hani M; Picozzi, Vincent; Chandana, Sreenivasa R; Melichar, Bohuslav; Kasi, Anup;

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  Philip, Philip; Ueno, Makoto; Van Cutsem, Eric; Seufferlein, Thomas; Macarulla, Teresa.

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  Reference:

  Journal Of Clinical Oncology 2025.

• Atezolizumab Plus Chemotherapy With or Without Bevacizumab in Advanced Biliary Tract Cancer: Clinical and Biomarker Data From the Randomized Phase II IMbrave151 Trial

  Macarulla, Teresa; Ren, Zhenggang; Chon, Hong Jae; Park, Joon Oh; Kim, Jin Won;

  (...)

  Liu, Bo; Guan, Xiangnan; Lu, Shan; Wang, Yulei; El-Khoueiry, Anthony B.

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  Reference:

  Journal Of Clinical Oncology 2025.

• Health-related quality of life and performance status with NALIRIFOX versus nab-paclitaxel + gemcitabine in treatment-naive patients with metastatic pancreatic ductal adenocarcinoma: results from the NAPOLI 3 trial

  Melisi D; Macarulla T; De La Fouchardière C; Pazo Cid RA; Chandana SR;

  (...)

  Maxwell F; Zhang L; Benzaghou F; O'Reilly EM; Wainberg ZA.

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  Reference:

  Esmo Open 2025.

• Clinical Value of Liquid Biopsy in Patients with FGFR2 Fusion-Positive Cholangiocarcinoma During Targeted Therapy

  Gonzalez-Medina, Alberto; Vila-Casadesus, Maria; Gomez-Rey, Marina; Fabregat-Franco, Carles; Sierra, Alexandre;

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  Miquel, Josep M; Nuciforo, Paolo; Perez-Lopez, Raquel; Macarulla, Teresa; Vivancos, Ana.

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  Reference:

  Clinical Cancer Research 2024.

• Facts and Hopes in the Systemic Therapy of Biliary Tract Carcinomas

  Lamarca, Angela; Macarulla, Teresa;

  Reference:

  Clinical Cancer Research 2024.

• Motixafortide and Pembrolizumab Combined to Nanoliposomal Irinotecan, Fluorouracil, and Folinic Acid in Metastatic Pancreatic Cancer: The COMBAT/KEYNOTE-202 Trial

  Bockorny, Bruno; Macarulla, Teresa; Semenisty, Valerya; Borazanci, Erkut; Feliu, Jaime;

  (...)

  Ickowicz, Debby; Sorani, Ella; Kadosh, Shaul; Vainstein-Haras, Abi; Hidalgo, Manuel.

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  Reference:

  Clinical Cancer Research 2021.