One in four people will have a mental health problem in their lifetime. To combat the stigma and myths associated with these disorders, the 2021 TV3 Marató Foundation focused on mental health. The final sum raised was 12,147,989 euros, which will be divided among the 36 research projects selected out of 150 proposals submitted.
Clínic-IDIBAPS researchers participate in fourteen of the projects selected:
- Glutamatergic neurotransmission and its correlates in brain structure and function during the neurodevelopmental trajectory leading to schizophrenia: from mice to humans
Funding: 297,978.50 euros
Researchers: Gisela Sugranyes Ernest, head of the IDIBAPS Multimodal neuroimaging in high risk and early psychosis; and Jordi Llop Roig of the CIC biomaGUNE Centre for Cooperative Research in Biomaterials.
Deciphering the clinical, neurobiological and genetic correlates of first episodes of mania in bipolar disorder: NOTION project
Funding: 399,699.25 euros
Researchers: Eduard Vieta Pascual, head of the IDIBAPS Bipolar and depressive disorders group and of the Psychiatry and Psychology Service at the Hospital Clínic; María Mur Laín, of the Biomedical Research Institute of Lleida (IRBLL) - Dr. Pifarré Foundation; Silvia Amoretti Guadall, of the Vall d’Hebron University Hospital Foundation - VHIR Research Institute; and Sergi Mas Herrero of the University of Barcelona Faculty of Medicine and Health Sciences.
Co-expression networks using DDR1 as a seed gene in blood and brain in bipolar disorder. Identification of new biomarkers
Funding: 399,606.25 euros
Researchers: Elisabet Vilella Cuadrada, of the Pere Mata Institute of Reus - Pere Virgili Health Research Institute Foundation; Regina Antoni Alandes, of the Josep Carreras Leukaemia Research Foundation Institute; Guadalupe Rivero Calera, of the Faculty of Medicine and Nursing, University of the Basque Country; and Anabel Martínez Aran, of the IDIBAPS Bipolar and depressive disorders group.
Naturalistic Study of Gene-Exposome Interaction in Bipolar Disorder (BEGIN)
Funding: 299,366.76 euros
Researchers: Andrea Murru, of the IDIBAPS Bipolar and depressive disorders group; and Léa Maitre, of the ISGLOBAL Barcelona Institute for Global Health Private Foundation.
Study of the hypothesis of accelerated aging in schizophrenia: analysis of epigenetic regulation in advanced age: the ENCLOSE-Age (EpigeNetic CLOck in SchizophrEnia- in Aged adults) Study
Funding: 137,447.31 euros.
Researchers: Rafael Penadés Rubio, of the IDIBAPS Schizophrenia group; and Bàrbara Segura Fàbregas, of the University of Barcelona Faculty of Medicine and Health Sciences.
Adaptation and implementation of a psycho-educational intervention for the prevention of postpartum depression and anxiety disorders in new mothers
Funding: 233,780 euros
Researchers: Alba Roca Lecumberri, head of the Hospital Clínic Perinatal Mental Health Unit; and Estel Gelabert Arbiol, of the Autonomous University of Barcelona Faculty of Psychology.
Prospective study of biomarkers and clinical predictors of long-term evolution and response to treatment in obsessive-compulsive disorder: the Barcelona cohort (B-OCDC).
Funding: 395,290.63 euros
Researchers: M. del Pino Alonso Ortega, of Bellvitge University Hospital; Carles Soriano Mas, of Bellvitge Biomedical Research Institute Foundation, IDIBELL; María Luisa Lázaro-García, of the IDIBAPS Child and adolescent psychiatry and psychology group; and Natalia Rodríguez Ferret, of the University of Barcelona Faculty of Medicine and Health Sciences.
Suicide as an extreme phenotype to understand suicidal behaviour: an approach based on the interaction of the genome with the epigenome
Funding: 376,384.29 euros
Researchers: Antoni Benabarre Hernández, of the IDIBAPS Bipolar and depressive disorders group; Bárbara Arias Sampériz, of the Bosch i Gimpera Foundation - University of Barcelona; and Thomas G. Schulze of the Institute of Psychiatric Phenomics and Genomics - Klinikum der Universtät München.
Retinal structure as a potential biomarker in schizophrenia disorders
Funding: 46,312.50 euros
Researcher: Miquel Bernardo Arroyo, head of the IDIBAPS Schizophrenia group.
Deep brain stimulation for patients with treatment-resistant schizophrenia: a prospective multicentre study
Funding: 297,296.25 euros
Researchers: Miquel Bioque Alcázar, of the IDIBAPS Schizophrenia group; and Salvador Sarró Maluquer, of the María Angustias Giménez Foundation for Research and Teaching (FIDMAG).
Depression: role and modulation of miRNAs in the anterior cingulate cortex as peripheral biomarkers and targets for promising nanotherapeutics
Funding: 380,900 euros
Researchers: Analia Bortolozzi Biassoni, head of the IDIBAPS Systems Neuropharmacology group; Cristina Fornaguera Puigvert, of the Chemical Institute of Sarrià - Ramon Llull University Foundation; and Francisco Javier de Diego Adeliño, of the Santa Creu i Sant Pau Institute Research Foundation.
Intervention and prevention treatment in suicide attempts: a randomised controlled trial
Funding: 204,600.01 euros
Researchers: María Dolores Braquehais Conesa, of the Vall d’Hebron University Hospital Foundation - VHIR Research Institute; and Pol Bruguera Soler, of the IDIBAPS Clinical addictions group.
Clinical, cognitive, epigenetic and neuroimaging characteristics of children and adolescents who are the children of patients with schizophrenia or bipolar disorder: creation of a predictive model of psychopathology and functioning over a ten-year period
Funding: 197,803.75 euros
Researcher: Josefina Castro Fornieles, head of the IDIBAPS Child and adolescent psychiatry and psychology group.
Non-invasive brain stimulation at home to treat treatment-resistant depression: feasibility, efficacy and biomarkers of treatment response
Funding: 298,850 euros
Researchers: Grabriele Cattaneo, of the Guttmann Institute Neurorehabilitation Hospital - Guttmann Institute Foundation; and David Bartrés Faz, of the IDIBAPS Neuropsychology group.