Gene therapy induces liver cancer in research animals

A subclass of liver cancers, meaning about 5 percent of cancers, could be initiated by oncogenic microRNA. A study published recently in Proceedings of the National Academy of Sciences (PNAS) shows that liver cancer is induced when overexpressing these microRNAs in an animal model. The work is a collaboration between the IDIBAPS - Hospital Clínic of Barcelona team led by Dr. Josep Maria Llovet, the Mount Sinai School of Medicine in New York and the University of Washington in Seattle (United States).