Genetic mechanisms of inflammation in chronic liver disease
Studies characterizing the genetic component that modifies the inflammatory response in these patients.
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Studies characterizing the genetic component that modifies the inflammatory response in these patients.
Studies discerning the mechanistic aspects of the inflammatory response in individual inflammatory cells, especially monocytes/macrophages.
Directed by Virginia Hernández Gea Her research centers on the role of endothelial dysfunction in the development of portal hypertension and porta...
Our team is involved in clinical trials to evaluate the efficacy and safety of several pharmacological agents, such as intranasal esketamine in add...
Directed by Sergi Castellví We identify common, low-penetrance genetic variants linked to colorectal cancer and/or advanced adenomas risk through...
Directed by Sergi Castellví We discover new genes for germline predisposition to colorectal cancer. We focus on studying familial (several cases i...
Directed by Leticia Moreira We find new genes for germline predisposition to gastric cancer by focusing on early-onset cases. As previously with c...
Directed by Sergi Castellví Candidate genes for colorectal cancer and gastric cancer are evaluated for their ability to predispose for these neopl...
Directed by Sergi Castellví We perform a genotype-phenotype correlation of the new genetic variants for germline predisposition to gastrointestina...
We work in the study of the mechanisms involved in the development of systemic inflammatory processes, the role of cell communication mediated by e...
We are studying the phosphoproteome, acetylome and ubiquitome of the primary T-cell searching for new substrates of modification involved in TCR-me...
Assessment of the clinical, biological and imaging factors involved in the pathogenesis of uveitic macular edema and its response to treatment.
Assessment of the efficacy and safety of new biologic therapies including anti-TNF-alpha, anti-IL-1beta, and anti-IL-6 receptor monoclonal antibodi...
Multicentric study that investigates genetic polymorphisms as potential risk factors for developing uveitis and its complications.
Development of epidemiological, clinical and experimental studies.
Development of clinical and experimental studies to investigate the pathogenesis of diabetic macular edema, as well as its response to different th...
Study of the contribution of chronic inflammation and in particular, C-reactive protein and complement Factor H to the progression of AMD.
Molecular genetics of glaucoma, proteomics of glaucoma secondary to uveitis, and applications of the structural analysis by OCT in glaucoma.
To create models to merge 3D images in the operating room in real time to detect lesions and improve diagnostic accuracy.
Radioligand therapy has proven to be useful in prostate cancer. Emerging indications for other prevalent tumors have opened a new path for oncologi...