Identification of candidates for and impact of percutaneous therapies for heart valve disease
We aim to understand the changes in valvular geometry and cardiac performance before and after implantation of novel percutanoeusly implanted devic...
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We aim to understand the changes in valvular geometry and cardiac performance before and after implantation of novel percutanoeusly implanted devic...
We explore the additive diagnostic value of several non-invasive cardiac imaging modalities for the identification of acute coronary syndrome among...
The loss of neuronal synapses is a phenomenon that occurs in the early stages of neurodegenerative disorders. We hypothesize that synaptic neurodeg...
Ab accumulation is a primary step of Alzheimer’s disease (AD). Noteworthy, while in early-onset familial AD increased Ab burden mainly results from...
Neuroinflammation is a key pathological feature of Alzheimer’s disease (AD) that results primarily from the presence of chronically activated micro...
The research line has been active for the last fourteen years. Both diseases are considered neurobiological disorders with an important genetic com...
Our group has studied clinical, neuropsychological and brain alterations in adolescents diagnosed with these disorders over the last fifteen years....
We study patients’ neuroimaging and genetic characteristics in order to differentiate endophenotypes and also use machine learning methodology to p...
Our group has published studies on cognitive and neuroimaging abnormalities in ASD children and adolescents and their siblings as well as ongenetic...
p27 (Kip1), a classical inhibitor of cyclin dependent kinases, is also a transcriptional regulator. We are analysing the mechanisms by which p27 re...
Our research focuses on identifying the molecular mechanism by which the CaMK family regulate cell cycle control and stress response. We are actual...
Multiple myeloma and systemic AL amyloidosis. Minimal residual disease, extramedullary involvement in myeloma, cardiac involvement in amyloidosis,...
Mechanisms of progression and control in patients with multiple myeloma. Molecular and cellular features of patients with long-lasting stable mon...
Natural history and prognosis of chronic myeloid leukemia, myeloproliferative neoplasms, acute myeloid leukemia and myelodysplastic syndromes; prog...
Lymphomas, chronic lymphocytic leukemia and the other lymphoproliferative disorders: Study of progression mechanisms of the disease, genome of CLL...
Based on our clinical and experimental studies on the development of osteoporosis in primary biliary cholangitis, we have confirmed its high preval...
We have analyzed the factors associated with the development of osteoporosis in men and in premenopausal women. These studies are important because...
For years we studied the characteristics of the bone pathology in patients before and after liver transplant. We recently evaluated whether the bon...
We have analyzed the OPG/RANKL system in different conditions: chronic cholestasis and patients with spinal cord injury. We have also analyzed aspe...
For years we have studied the effectiveness of the use of bone turnover markers to analyze the activity of Paget's bone disease. We recently extend...