Search results

• Impact of lifestyle on diabetes

  Diabetes is a serious global health problem due to its prevalence (more than 425 million people), the economic burden and the number of deaths it c...

  Research – Research lines

• Circulating microRNAs as potential biomarkers and therapeutic targets in type 2 diabetes

  We are interested in finding circulating microRNAs as biomarkers for prediabetes and diabetes, for its micro- and macrovascular complications and f...

  Research – Research lines

• New therapeutic targets for the treatment of type 2 diabetes and obesity

  The molecular mechanisms underlying the onset and progression of type 2 diabetes is crucial to find novel targets and therapeutic strategies to tre...

  Research – Research lines

• Mechanisms and treatment of endothelial dysfunction in type 2 diabetes

  Diabetes has a detrimental impact on endothelial cell function. In this context, we investigate the impact of glucose oscillations on cardiovascula...

  Research – Research lines

• Bacteremia

  We have been prospectively collecting data on all episodes of bacteremia in the hospital since 1990. This makes it possible to analyze the epidemio...

  Research – Research lines

• Immunocompromised patients

  Register of patients with blood cancer undergoing chemotherapy or bone-marrow transplant. The main areas of study are infections by multiresistant...

  Research – Research lines

• Bone and joint infections

  European Register of Infections/AIDS on joint prostheses, aimed at studying diagnostic methods and the efficacy of new antibiotics in this type of...

  Research – Research lines

• Intestinal microbiota

  We are developing a system to make it possible to perform fecal transplants from healthy volunteers to patients with Clostridium difficile and whic...

  Research – Research lines

• Characterization of the functional impact of driver mutations and the analysis of new potential therapeutic approaches

  Genetic studies have led to the identification of novel recurrent somatic mutations with predicted functional impact, offering new potential therap...

  Research – Research lines

• Development of predictive models recapitulating tumor heterogeneity and their impact on disease evolution, therapy resistance and susceptibility to novel targeted therapies

  Due to the high heterogeneity and complexity of B lymphoid malignancies, the analysis of the effect of novel targeted drugs in different mutational...

  Research – Research lines

• Mechanisms of resistance to targeted therapy

  Treatment with novel targeted drugs like the Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib or the Bcl-2 antagonist venetoclax improved outcome...

  Research – Research lines

• Prevention and treatment of chronic liver diseases

  Directed by Pere Ginès This line focuses on risk factors and early diagnosis of chronic liver diseases in the general population. It defines liver...

  Research – Research lines

• Pathogenic mechanisms of alcohol-related liver disease, effects of abstinence, and novel therapies

  Directed by Elisa Pose This established line combines clinical and translational research on alcohol-related liver disease. It includes independen...

  Research – Research lines

• Mechanisms of disease progression and risk stratification in metabolic dysfunction-associated steatotic liver disease

  Directed by Isabel Graupera This line studies how metabolic dysfunction drives MASLD progression and supports risk stratification for personalized...

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• Translational liver cell biology and disease mechanisms in chronic liver disease

  Directed by Mar Coll This translational line focuses on liver inflammation and cellular mechanisms underlying chronic liver disease progression. I...

  Research – Research lines

• Sleep and sleep disorders

  A clinical and electrophysiological assessment of normal sleep in humans and of sleep disorders including the anti-IgLON5 disease, REM sleep behavi...

  Research – Research lines

• Epilepsy

  Characterization of the epileptogenic activity and the surgical and medical therapy of the refractory epilepsy using functional MRI, video-EEG and...

  Research – Research lines

• Neuropathic pain

  Electrophysiological evaluation of the neuropathic pain using nocioceptive evoked potentials and other tools including the startle reaction.

  Research – Research lines

• Motor control

  Assesment of the motor control in healthy subjects and in patients with neurological diseases using acoustic and somatosensorial stimul and prepulse.

  Research – Research lines

• Precision screening, diagnosis, and staging for enhanced liver cancer outcomes

  Directed by Maria Reig  Effective stratification of patients according to their cancer risk is essential to ensure cost-effective screening progra...

  Research – Research lines