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Showing 5621 - 5640 de 10501 results

  • Cellular immunotherapy for the treatment of cancer and other immune-mediated diseases

    Directed by Dr. Daniel Benítez Development of mainly cell therapies based primarily on dendritic cells (vaccines ) directly isolated or monocyte-d...

    Research – Research lines
  • Molecular and epigenetic mechanisms responsible for the persistent deleterious effects in target tissue exposed to steroidal hormones

    Translational approach in humans and animal models.

    Research – Research lines
  • Neural correlates of mood- and anxiety-related disorders

    Directed by Joaquim Raduà We employ several neuroimaging modalities (e.g., structural, DTI, functional connectivity, fMRI) to investigate the brai...

    Research – Research lines
  • Development of neuroimaging-based diagnostic and treatment prediction tools

    Directed by Joaquim Raduà We are working on the development and validation of imaging-based machine-learning models to improve the diagnosis and o...

    Research – Research lines
  • Evidence-based syntheses in mental health

    Directed by Joaquim Raduà We conduct syntheses (e.g., meta-analyses, mega-analyses and umbrella reviews) of variables and processes involved in me...

    Research – Research lines
  • Integrative genetic profile and identification diagnostic markers

    In order to achieve the complete global genetic landscape of these rare tumors we are studying the molecular profile of poorly characterized Non-Ho...

    Research – Research lines
  • Study of intratumoral heterogeneity

    Data already obtained in the analysis of pediatric NHL shows the presence of intratumoral heterogeneity that may represent the existence of differe...

    Research – Research lines
  • Identification of genetic biomarkers and drug targets

    Our final goal is to identify target genes/pathways that can be useful biomarkers in the management of pediatric NHL. In detail, we aim to identify...

    Research – Research lines
  • 1. Ischemia-reperfusion injury and expanding criteria for liver graft acceptance

    Maintaining the viability of organs from their recovery to transplantation is a key factor for transplant success and graft survival. Organ damage...

    Research – Research lines
  • 2. Endoscopic management of biliary complications following liver transplantation

    The study of biliary complications after liver transplantation has high clinical relevance, due it relatively high incidence, complexity of managem...

    Research – Research lines
  • 3. Expanding indications for liver transplantation in relation to pre-existing portal vein thrombosis and portal hypertension

    It is widely known that portal vein thrombosis is a serious complication of chronic liver disease, and the prognosis of liver transplantation depen...

    Research – Research lines
  • 4. Expanding indications for transplantation for malignant tumors – hilar cholangiocarcinoma and colorectal cancer liver metastases

    The decrease in the number of patients on liver transplant waiting lists due to the advent of effective treatment for hepatitis C virus has generat...

    Research – Research lines
  • 5. Alloimmune response, complications associated with immunosupression, and operational tolerance

    Treatment with immunosupression is associated with a series of risks for the transplanted patient, making minimization key to optimizing post-trans...

    Research – Research lines
  • 6. Prevention and treatment of cardiovascular risk factors following liver transplantation

    Cardiovascular diseases represent one of the most common causes of long-term morbidity and mortality after liver transplantation. This group focuse...

    Research – Research lines
  • Clinical applicability of genomic copy-number alterations and aneuploidy

    Chromosomal aneuploidy results in the acquisition of copy-number alterations, which occur early in tumorigenesis and are positively selected throug...

    Research – Research lines
  • Intratumor heterogeneity as a novel biomarker in colorectal cancer

    Elucidating the role of genomic instability, which represents the molecular engine that fuels intratumor heterogeneity in carcinomas, is critical f...

    Research – Research lines
  • Functional consequences of whole-genome doubling and its impact on disease outcome

    There is growing evidence that whole-genome doubling occurs early in tumorigenesis and triggers genetically unstable near-tetraploid cells. In addi...

    Research – Research lines
  • 1-Which is the role of translational control of gene expression in liver disease and cancer?

    To understand the molecular mechanisms involved in the development and progression of liver disease and cancer, with a focus on the aberrant reprog...

    Research – Research lines
  • 2-What is the significance and underlying mechanisms linking obesity with liver disease and cancer?

    To decipher mechanisms underpinning the detrimental impact of obesity in liver disease and cancer. This knowledge is crucial for advancements in tr...

    Research – Research lines
  • 3-How does deregulation of pathways that control angiogenesis contribute to progression of liver disease and cancer?

    To define the molecular and cellular mechanisms that regulate/dysregulate angiogenesis in liver disease and cancer and define their functional rele...

    Research – Research lines

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