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• Aging & liver diseases

  Considering the increase in worldwide population median age and life expectancy, we devote a significant part of our resources at characterizing, i...

  Research – Research lines

• Molecular pathology of B-cell neoplasms

  Directed by Elías Campo To characterize the molecular alterations involved in the development and progression of lymphoid neoplasms, particularly...

  Research – Research lines

• Oncogene mediated genome instability and transcriptional stress in the progression of lymphoid neoplasms

  Directed by Pedro Jares Our research focuses on understanding the molecular mechanisms behind the genomic instability and transcriptional dysregul...

  Research – Research lines

• Non-coding RNA alterations in the pathogenesis on B-cell lymphoid neoplasms

  Directed by Lluis Hernández We focus on finding non-coding RNAs (mainly microRNAs and long non-coding RNAs) as biomarkers of interest in the clini...

  Research – Research lines

• MRI and genetic markers of multiple sclerosis long-term progression

  Observational study to explore the biology of progression in multiple sclerosis using genetic approaches coupled with neuroimage-based tissue pheno...

  Research – Research lines

• Cognitive rehabilitation and brain plasticity in multiple sclerosis

  A randomized controlled clinical study: Study to evaluate the efficacy of cognitive rehabilitation in patients with multiple sclerosis that presen...

  Research – Research lines

• Structural connectivity in multiple sclerosis

  Multicentric study within MAGNIMS group. This project is designed to provide high quality information on the changes in structural connectivity in...

  Research – Research lines

• Network mechanisms of working memory in the prefrontal cortex

  We combine computational model simulations with data analysis of electrophysiological single-neuron recordings from collaborating laboratories in o...

  Research – Research lines

• The role of NMDARs in working memory

  We are investigating the specific deficits in working memory of patients recovering from anti-NMDAR encephalitis. We study their behavioral paramet...

  Research – Research lines

• The role of NMDARs in slow-wave sleep

  We investigate sleep patterns in anti-NMDAR encephalitis patients by recording polysomnogram and EEG longitudinally as patients recover from the di...

  Research – Research lines

• The NMDAR hypothesis of schizophrenia

  NMDAR hypofunction has been hypothesized as a possible mechanism of schizophrenia. By comparing behavioral, EEG and fMRI parameters between anti-NM...

  Research – Research lines

• The multifaceted mitochondria: obesity, diabetes and beyond

  Directed by Marc Claret  We have several projects aimed at understanding neuron-type specific mitochondrial biology, from many different angles (d...

  Research – Research lines

• Cell-type specific epigenetics and obesity

  Directed by Marc Claret  We use cutting-edge genetic models to unravel the epigenetic landscape of specific subpopulations of neurons under obesog...

  Research – Research lines

• Endothelial cells: new players in metabolic disorders

  Directed by Marc Claret  We are also interested in understanding the influence of endothelial cells in systemic metabolic control and in the devel...

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• Neuronal Heterogeneity and Functional Specialization

  Directed by Marc Claret  Our research focuses on understanding how neuronal heterogeneity within key hypothalamic circuits contributes to the prec...

  Research – Research lines

• Endophenotypes, genetics and biomarkers of affective disorders

  Our group is involved in national and international projects that are contributing to important advances in the field of the genetic and epigenetic...

  Research – Research lines

• Epidemiology and disability associated with bipolar and unipolar disorders

  Affective disorders are among the leading causes of disability worldwide, and the development of treatments aimed to prevent or diminish functional...

  Research – Research lines

• First affective and psychotic episodes

  Our group is focused on early intervention as a critical paradigm for improving disease outcomes, via the evaluation of patients with first episode...

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• Innovative psychological interventions for bipolar disorder and depression

  Our group has developed novel psychological interventions for the treatment of affective disorders, i.e. psychoeducation, family intervention, func...

  Research – Research lines

• Neurocognition and neuroimaging of bipolar and unipolar disorders

  The group has been a pioneer in the characterization of the neurocognitive alterations associated with affective disorders, both in hot and cold co...

  Research – Research lines