Search results

• Cell-type specific epigenetics and obesity

  Directed by Marc Claret  We use cutting-edge genetic models to unravel the epigenetic landscape of specific subpopulations of neurons under obesog...

  Research – Research lines

• Endothelial cells: new players in metabolic disorders

  Directed by Marc Claret  We are also interested in understanding the influence of endothelial cells in systemic metabolic control and in the devel...

  Research – Research lines

• Neuronal Heterogeneity and Functional Specialization

  Directed by Marc Claret  Our research focuses on understanding how neuronal heterogeneity within key hypothalamic circuits contributes to the prec...

  Research – Research lines

• Endophenotypes, genetics and biomarkers of affective disorders

  Our group is involved in national and international projects that are contributing to important advances in the field of the genetic and epigenetic...

  Research – Research lines

• Epidemiology and disability associated with bipolar and unipolar disorders

  Affective disorders are among the leading causes of disability worldwide, and the development of treatments aimed to prevent or diminish functional...

  Research – Research lines

• First affective and psychotic episodes

  Our group is focused on early intervention as a critical paradigm for improving disease outcomes, via the evaluation of patients with first episode...

  Research – Research lines

• Innovative psychological interventions for bipolar disorder and depression

  Our group has developed novel psychological interventions for the treatment of affective disorders, i.e. psychoeducation, family intervention, func...

  Research – Research lines

• Neurocognition and neuroimaging of bipolar and unipolar disorders

  The group has been a pioneer in the characterization of the neurocognitive alterations associated with affective disorders, both in hot and cold co...

  Research – Research lines

• Observational studies in affective disorders

  Our group has led sevral observational studies in bipolar disorder and in depressed patients (such as the BRIDGE study) with recent focus on treatm...

  Research – Research lines

• Psychometrics of mental disorders

  In addition, the research team has developed new clinical scales for the screening of affective disorders and the assessment of cognitive impairmen...

  Research – Research lines

• Pathophysiology, diagnosis and treatment of portal hypertension

  Directed by Juan Carlos García‑Pagán His research research is centered on the pathophysiology, diagnosis and treatment of portal hypertension and...

  Research – Research lines

• Mechanisms of liver inflammation and fibrosis

  Chronic liver injury is characterized by an important inflammatory response and an increase in extracellular matrix deposition, which may lead to l...

  Research – Research lines

• Liver cell plasticity

  The liver has remarkable cell plasticity. Lineage tracing studies have shown the potential of biliary-to-hepatocyte as well as hepatocyte-to-biliar...

  Research – Research lines

• In vitro disease modeling

  In vitro liver models have emerged as excellent tools to better understand liver pathology, to test new therapeutic drugs and for toxicity testing...

  Research – Research lines

• Pharmacological, technological and surgical strategies in liver transplantation and surgery

  1. Effect of brain death on steatotic and non-steatotic livers undergoing transplantation Preclinical studies will be carried out to investigate t...

  Research – Research lines

• A new medical device for transporting abdominal organs in clinical practice

  We intend to develop a new organ transport device which uses a revolutionary technology leading to superior preservation of the organs during trans...

  Research – Research lines

• New preservation solutions in liver transplantation

  The research carried out by our group to improve the composition of preservation solutions has culminated in the granting of a patent, which has be...

  Research – Research lines

• Innovations for organ preservation during long times

  Organs and other biological specimens have traditionally been fixed in formaldehyde, which negatively affect many of their intrinsic properties and...

  Research – Research lines

• To study the regulatory mechanisms and efficacy of stem cell therapy in experimental models and in clinical contexts

  We aim to evaluate the efficacy and safety of stent cell therapy in experimental models of acute and chronic ischemia.

  Research – Research lines

• To perform experimental models of neointimal hyperplasia, endothelialization, vascular inflammation and thrombosis

  We aim to assess the inflammatory response leading to thrombosis and endothelial healing after coronary injury or therapeutic procedures in experim...

  Research – Research lines