Search results

• Ethics in clinical research

  Search for quality and the extent and context of application of current ethical principles in clinical research projects. It is developed in group...

  Research – Research lines

• Pharmacogenetics and pharmacogenomics

  Development of studies to relate genetics with the activity and response to the action of drugs.

  Research – Research lines

• Coordination of multinational projects and research networks

  Active collaboration in national clinical research networks, such as SCReN (Spanish clinical Research Network), to carry out multicenter clinical r...

  Research – Research lines

• Etiopathogenesis in endometriosis and adenomyosis

  Directed by: Maria Angels Martínez Zamora To evaluate new insights in the knowledge of the origin and recurrence of endometriosis and adenomyosis...

  Research – Research lines

• Human papillomavirus (HPV) infection and prevention

  Directed by: Marta del Pino To understand the natural history of HPV infection will allow us to improve both prevention strategies and related les...

  Research – Research lines

• Interplay between HBV, HDV and host factors: impact on liver disease progression

  Hepatitis delta is caused by infection with the hepatitis D virus (HDV) and is considered to be the most severe form of human viral hepatitis. Chro...

  Research – Research lines

• Glutamatergic signalling: functional interaction between AMPARs, auxiliary subunits and novel interacting proteins

  Physiological characterization of AMPAR and interacting proteins (TARPs and CPT1C) in neurons and glial cells and the role in memory and sensibilit...

  Research – Research lines

• Pathophysiology of the NMDAR receptor and personalised medicine for GRIN-related disorders.

  Functional studies of NMDAR receptors with new block synthesis compounds and positive allosteric modulators in the framework of neurological diseases.

  Research – Research lines

• Ocular physiology: dry eye physiopathology and sensory neurons on the ocular surface. Pathophysiology of the drainage of aqueous humour and the physiopathology of glaucoma

  Study of the ionic channels involved in the detection of painful and irritating stimuli on the ocular surface and its role in eye pathologies such...

  Research – Research lines

• Physiology and pathophysiology of pain and chronic itch. Study of the ion channels involved in neuronal excitability in the sensory nervous system

  Study of the ionic channels that regulate the electrical activity of sensory neurons and how they are altered during the pathology. Identification...

  Research – Research lines

• Microglia-neuron crosstalk in health and disease

  To understand how neuron-glia communication contributes to synapse and neuronal loss, and modulates neuronal activity in neurodegeneration. A majo...

  Research – Research lines

• N-glycosilation channelopathies and synaptic function

  Investigation how the activity of synaptic proteins and the synaptic function is affected by physiological and pathological N-glycosylation and its...

  Research – Research lines

• Utility of ECG imaging in locating abnormal conduction zones and in mapping arrhythmias.

  This involves obtaining images of the heart’s electrical activity in a noninvasive manner in order to apply this knowledge to developing ablation s...

  Research – Research lines

• Role of stimulation of the conduction system in cardiac stimulation.

  Study of new physiologic stimulation techniques. Assessment of results and complications. 

  Research – Research lines

• Study of the utility of new mapping tools in ablation of ventricular tachycardia

  Treatment of ventricular tachycardia requires detailed mapping of the circuits. Currently, catheters are used that are more accurate than is requir...

  Research – Research lines

• Biomarkers, transplant immunology and cell therapy in renal and pancreatic transplantation.

  Directed by Dr. Fritz Diekmann and Dr. Pedro Ventura In the last years we have worked with exosomes, Chimeric antigen receptor-T cells (CAR-Ts), M...

  Research – Research lines

• New technologies and biomarkers in dialysis

  Directed by Dr. Francesc Maduell During the last years we analyzed and improved the quality of dialysis, especially studying vascular calcificatio...

  Research – Research lines

• Pathophisiology and innovative therapies in acute and chronic kidney disease

  Directed by Dr. Luis F Quintana and Dr Miquel Blasco. We were studying endothelial dysfunction and complement disorders in the context of chronic...

  Research – Research lines

• Artificial intelligence

  Directed by Dr. Ignacio Revuelta We are developing predictive AI models that classify patients in terms of their immunological risk and, consequen...

  Research – Research lines

• Novel biomarkers and clinical relevance of the persistence of cccDNA in chronic HBV infection

  There is no curative treatment for HBV infection. This is mainly due to the persistence of cccDNA (covalently closed circular DNA) in the nucleus o...

  Research – Research lines